SCHEMBL29533359

SCHEMBL29533359

N=C(N)NCCC[C@H](NC(=O)CNC(=O)[C@@H](N)CCCNC(=N)N)C(=O)NCC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.44
GSTK1 Q9Y2Q3 1/20 0.44
NPY4R P50391 14/20 0.42
NPY1R P25929 8/20 0.42
NPY5R Q15761 6/20 0.42
NPY2R P49146 5/20 0.42
GLO1 Q04760 1/20 0.42
NOD1 Q9Y239 2/20 0.41
DPP7 Q9UHL4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29655812 1.00 PTGS1 (0.44) PTGS1GSTK1NPY4RNPY1RNPY5R
SCHEMBL29655852 1.00 PTGS1 (0.44) PTGS1GSTK1NPY4RNPY1RNPY5R
SCHEMBL29655840 1.00 PTGS1 (0.44) PTGS1GSTK1NPY4RNPY1RNPY5R
SCHEMBL29655791 1.00 PTGS1 (0.44) PTGS1GSTK1NPY4RNPY1RNPY5R
SCHEMBL29590332 0.98 PTGS1 (0.43) PTGS1GSTK1NPY4RNPY1RNPY5R
SCHEMBL19791172 0.95 PTGS1 (0.41) PTGS1GSTK1NPY4RNPY1RNPY5R
SCHEMBL30254242 0.94 GNAI3 (0.43) PTGS1GSTK1NPY4RNPY1RNPY5R
SCHEMBL7306618 0.93 PTGS1 (0.43) PTGS1GSTK1NPY4RNPY1RNPY5R
SCHEMBL29630413 0.93 PTGS1 (0.43) PTGS1GSTK1NPY4RNPY1RNPY5R
SCHEMBL31691755 0.92 NPY4R (0.44) PTGS1GSTK1NPY4RNPY1RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2025-06-12 US claimed
EP-3704143-B1 CHEMO-ENZYMATIC SYNTHESIS OF LIRAGLUTIDE, SEMAGLUTIDE AND GLP-1 FRESENIUS KABI IPSUM S R L (IT) 2023-10-18 EP claimed
US-12600759-B2 Process of preparation of glucagon-like peptide-1 (GLP-1) receptor agonists and their analogs ENZENE BIOSCIENCES LIMITED (IN) 2026-04-14 US disclosed
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2025-06-12 US disclosed
WO-2025093774-A1 GLUCAGON-LIKE PEPTIDE 1 AGONISTS Constructive Biology Limited (GB) 2025-05-08 WO disclosed
US-20250074964-A1 STABLE GLP-1 ANALOGS FOR THE TREATMENT OF HUMAN DISEASE AND DISORDERS Ambio, Inc. 2025-03-06 US disclosed
CN-116120427-B Semex lattice Synthesis method of lupeptide 浙江九洲药业股份有限公司 2024-12-10 CN disclosed
WO-2024159569-A1 METHOD FOR SYNTHESIZING SEMAGLUTIDE 浙江九洲药业股份有限公司 2024-08-08 WO disclosed
US-20240150423-A1 GLP-1 ANALOGUE-MODIFIED DIMERS WITH DIFFERENT CONFIGURATIONS, PREPARATION METHOD THEREOF, AND APPLICATION THEREOF IN TREATMENT OF TYPE II DIABETES Nanjing Finepeptide Biopharmaceutical Co.,Ltd (CN) 2024-05-09 US disclosed
WO-2024068827-A1 METHOD FOR PREPARING LIRAGLUTIDE BACHEM HOLDING AG (CH) 2024-04-04 WO disclosed
CN-117402256-A Protein dimers consisting of GLP-1 and EGF (A) analogues 乐普(北京)医疗器械股份有限公司 2024-01-16 CN disclosed
CN-117202936-A Glucagon-like peptide compounds 诺华股份有限公司 2023-12-08 CN disclosed
CN-116120427-A Synthesis method of semaglutin 浙江九洲药业股份有限公司 2023-05-16 CN disclosed
WO-2023012709-A1 AN IMPROVED PROCESS FOR FMOC SYNTHESIS OF SEMAGLUTIDE USV PRIVATE LIMITED (IN) 2023-02-09 WO disclosed
US-20220153804-A1 PROCESS OF PREPARATION OF GLUCAGON-LIKE PEPTIDE-1 (GLP-1) RECEPTOR AGONISTS AND THEIR ANALOGS ENZENE BIOSCIENCES LIMITED (IN) 2022-05-19 US disclosed
CN-110818775-B Protein and polypeptide protective agent and application thereof 北京双鹭药业股份有限公司 2022-05-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150423-A1 GLP-1 ANALOGUE-MODIFIED DIMERS WITH DIFFERENT CONFIGURATIONS, PREPARATION METHOD THEREOF, AND APPLICATION THEREOF IN TREATMENT OF TYPE II DIABETES GLP1R, IAPP, GCG PTGS1 732/4885GSTK1 632/4885NPY4R 77/4885
US-20220153804-A1 PROCESS OF PREPARATION OF GLUCAGON-LIKE PEPTIDE-1 (GLP-1) RECEPTOR AGONISTS AND THEIR ANALOGS GLP1R, GIPR, GCGR PTGS1 2797/4885GSTK1 4387/4885NPY4R 14/4885
US-12600759-B2 Process of preparation of glucagon-like peptide-1 (GLP-1) receptor agonists and their analogs GLP1R, GIPR, GCG PTGS1 4230/4885GSTK1 3704/4885NPY4R 43/4885
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE GLP1R, IAPP, GCG PTGS1 3170/4885GSTK1 2586/4885NPY4R 52/4885
US-20250074964-A1 STABLE GLP-1 ANALOGS FOR THE TREATMENT OF HUMAN DISEASE AND DISORDERS GLP1R, GIPR, GPR119 PTGS1 3684/4885GSTK1 2195/4885NPY4R 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.