SCHEMBL29533485

SCHEMBL29533485

Cc1cn(C2CC(O)C(COP(=O)(O)OC3CC(n4cnc5c(=O)[nH]c(N)nc54)OC3COP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.63

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 2/20 0.63
▸ POLB P06746 2/20 0.62
▸ TERT O14746 2/20 0.60
▸ P2RY2 P41231 1/20 0.60
▸ P2RY4 P51582 1/20 0.60
▸ P2RY6 Q15077 1/20 0.60
▸ DTYMK P23919 4/20 0.59
▸ TK1 P04183 3/20 0.54
▸ FUT5 Q11128 1/20 0.52
▸ TYMS P04818 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29534179 1.00 F2 (0.63) F2POLBTERTP2RY2P2RY4
SCHEMBL29671382 0.96 F2 (0.68) F2POLBTERTP2RY2P2RY4
SCHEMBL29350192 0.96 F2 (0.68) F2POLBTERTP2RY2P2RY4
SCHEMBL29415903 0.96 F2 (0.68) F2POLBTERTP2RY2P2RY4
SCHEMBL29775052 0.96 F2 (0.68) F2POLBTERTP2RY2P2RY4
SCHEMBL34463741 0.96 F2 (0.68) F2POLBTERTP2RY2P2RY4
SCHEMBL29369996 0.94 F2 (0.62) F2POLBTERTP2RY2P2RY4
SCHEMBL29372542 0.94 F2 (0.62) F2POLBTERTP2RY2P2RY4
SCHEMBL29357819 0.94 F2 (0.62) F2POLBTERTP2RY2P2RY4
SCHEMBL30211177 0.94 F2 (0.62) F2POLBTERTP2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3674404-B1 TARGET SEQUENCE SPECIFIC ALTERATION TECHNOLOGY USING NUCLEOTIDE TARGET RECOGNITION UNIV TOKUSHIMA (JP) 2025-10-15 — — EP claimed
US-12247200-B2 Compositions and methods for generating massively parallel nucleic acid sequencing libraries BIOO SCIENTIFIC CORPORATION (US) 2025-03-11 — — US claimed
US-12215315-B2 Method for modifying target nucleic acid in genome of cell INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2025-02-04 — — US claimed
US-20240327828-A1 TARGET SEQUENCE SPECIFIC ALTERATION TECHNOLOGY USING NUCLEOTIDE TARGET RECOGNITION UNIV TOKUSHIMA (JP) 2024-10-03 — — US claimed
US-12012596-B2 Target sequence specific alteration technology using nucleotide target recognition TOKUSHIMA UNIVERSITY (JP) 2024-06-18 — — US claimed
CN-116381228-A Reagent for capturing and detecting circulating exosomes and application thereof 上海大学 2023-07-04 — — CN claimed
CN-114667149-A Novel nucleobase editor and methods of use 比姆医疗股份有限公司 2022-06-24 — — CN claimed
WO-2026099341-A1 BIOCONTAINMENT OF UNWANTED ENGINEERED CELLS USING NON-NATURAL AMINO ACIDS SNIPR BIOME APS (DK) 2026-05-15 — — WO disclosed
US-20260085315-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER APTAH BIO INC (US) 2026-03-26 — — US disclosed
US-20260022377-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASES APTAH BIO INC (US) 2026-01-22 — — US disclosed
EP-4652277-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASES Aptah Bio, Inc. (US) 2025-11-26 — — EP disclosed
EP-4652278-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER Aptah Bio, Inc. (US) 2025-11-26 — — EP disclosed
EP-3674404-B1 TARGET SEQUENCE SPECIFIC ALTERATION TECHNOLOGY USING NUCLEOTIDE TARGET RECOGNITION UNIV TOKUSHIMA (JP) 2025-10-15 — — EP disclosed
CN-116096873-A Methods and compositions for editing two strands of a target double-stranded nucleotide sequence simultaneously 布罗德研究所股份有限公司 2023-05-09 — — CN disclosed
US-20230047776-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR GENE EXPRESSION REGULATIONS APTAH BIO, INC. 2023-02-16 — — US disclosed
WO-2023288111-A2 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR GENE EXPRESSION REGULATION APTAH BIO, INC. (US) 2023-01-19 — — WO disclosed
CN-114667149-A Novel nucleobase editor and methods of use 比姆医疗股份有限公司 2022-06-24 — — CN disclosed
US-11365452-B2 Composition for diagnosing or predicting risk of metabolic syndrome or metabolic syndrome-related diseases using human oral microbiome KOBIOLABS, INC. (KR) 2022-06-21 — — US disclosed
WO-2022075419-A1 TECHNIQUE FOR MODIFYING TARGET NUCLEOTIDE SEQUENCE USING CRISPR-TYPE I-D SYSTEM 国立大学法人徳島大学 2022-04-14 — — WO disclosed
EP-3978624-A1 METHYLATED CONTROL DNA Exact Sciences Corporation (US) 2022-04-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085315-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER RPRD2, RTCB, UPF1 F2 3290/4885POLB 224/4885TERT 723/4885
US-20260022377-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASES PRNP, UPF1, FUS F2 1620/4885POLB 387/4885TERT 397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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