SCHEMBL34463741

SCHEMBL34463741

Cc1cn(C2CC(OP(=O)(O)OCC3OC(n4cnc5c(=O)[nH]c(N)nc54)CC3OP(=O)(O)OCC3OC(n4cnc5c(=O)[nH]c(N)nc54)CC3O)C(COP(=O)(O)OC3CC(n4cc(C)c(=O)[nH]c4=O)OC3COP(=O)(O)OC3CC(n4cnc5c(=O)[nH]c(N)nc54)OC3COP(=O)(O)OC3CC(n4cnc5c(=O)[nH]c(N)nc54)OC3COP(=O)(O)OC3CC(n4cc(C)c(=O)[nH]c4=O)OC3COP(=O)(O)OC3CC(n4cnc5c(=O)[nH]c(N)nc54)OC3COP(=O)(O)OC3CC(n4cc(C)c(=O)[nH]c4=O)OC3COP(=O)(O)OC3CC(n4cnc5c(=O)[nH]c(N)nc54)OC3COP(=O)(O)OC3CC(n4cnc5c(=O)[nH]c(N)nc54)OC3COP(=O)(O)OC3CC(n4cc(C)c(=O)[nH]c4=O)OC3COP(=O)(O)OC3CC(n4cc(C)c(=O)[nH]c4=O)OC3COP(=O)(O)OC3CC(n4cnc5c(=O)[nH]c(N)nc54)OC3COP(=O)(O)OC3CC(n4cnc5c(=O)[nH]c(N)nc54)OC3CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.68

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 5/20 0.68
▸ POLB P06746 2/20 0.60
▸ TERT O14746 2/20 0.59
▸ P2RY2 P41231 1/20 0.59
▸ P2RY4 P51582 1/20 0.59
▸ P2RY6 Q15077 1/20 0.59
▸ DTYMK P23919 4/20 0.58
▸ FUT5 Q11128 1/20 0.51
▸ TK1 P04183 2/20 0.49
▸ TYMS P04818 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29415903 1.00 F2 (0.68) F2POLBTERTP2RY2P2RY4
SCHEMBL29350192 1.00 F2 (0.68) F2POLBTERTP2RY2P2RY4
SCHEMBL29671382 1.00 F2 (0.68) F2POLBTERTP2RY2P2RY4
SCHEMBL29775052 1.00 F2 (0.68) F2POLBTERTP2RY2P2RY4
SCHEMBL15672415 0.97 F2 (0.65) F2POLBTERTP2RY2P2RY4
SCHEMBL29534179 0.96 F2 (0.63) F2POLBTERTP2RY2P2RY4
SCHEMBL29533485 0.96 F2 (0.63) F2POLBTERTP2RY2P2RY4
SCHEMBL29408579 0.95 F2 (0.62) F2POLBTERTP2RY2P2RY4
SCHEMBL23009655 0.95 DTYMK (0.67) F2POLBTERTP2RY2P2RY4
SCHEMBL30103510 0.95 DTYMK (0.67) F2POLBTERTP2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606830-B2 Protected antibody-drug and aptamer-drug conjugates KOSAK KENNETH MICHAEL (US) 2026-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606830-B2 Protected antibody-drug and aptamer-drug conjugates PABPC1, PABPC4, ABCG2 F2 4831/4885POLB 636/4885TERT 836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback