SCHEMBL29533710

SCHEMBL29533710

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nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 15/20 0.46
CTSD P07339 4/20 0.46
NOD1 Q9Y239 2/20 0.44
FOLH1 Q04609 1/20 0.43
BACE2 Q9Y5Z0 2/20 0.42
DPP4 P27487 1/20 0.41
DPP8 Q6V1X1 1/20 0.41
DPP9 Q86TI2 1/20 0.41
ENPEP Q07075 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30477363 0.97 BACE1 (0.46) BACE1CTSDNOD1FOLH1BACE2
SCHEMBL29376100 0.95 BACE1 (0.48) BACE1CTSDNOD1FOLH1BACE2
SCHEMBL29765278 0.94 BACE1 (0.48) BACE1CTSDNOD1FOLH1BACE2
SCHEMBL30768075 0.94 BACE1 (0.48) BACE1CTSDNOD1FOLH1BACE2
SCHEMBL31429591 0.90 FOLH1 (0.48) NOD1FOLH1DPP4DPP8DPP9
SCHEMBL29886748 0.89 BACE1 (0.53) BACE1CTSDBACE2
SCHEMBL38659209 0.88 NMT2 (0.45) BACE1CTSDFOLH1BACE2
SCHEMBL30767177 0.88 NOD1 (0.49) BACE1CTSDNOD1DPP4DPP8
SCHEMBL30767162 0.88 NOD1 (0.49) BACE1CTSDNOD1DPP4DPP8
SCHEMBL30193334 0.88 FOLH1 (0.46) NOD1FOLH1DPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12540161-B2 Linkers BICYCLETX LIMITED (GB) 2026-02-03 US disclosed
CN-116348476-A Peptide-based linkers 拜斯科技术开发有限公司 2023-06-27 CN disclosed
EP-4188938-A1 PEPTIDE-BASED LINKERS BicycleTX Limited (GB) 2023-06-07 EP disclosed
WO-2022029420-A1 PEPTIDE-BASED LINKERS BICYCLETX LIMITED (GB) 2022-02-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540161-B2 Linkers ADM2, CDA, DCTD BACE1 1756/4885CTSD 2009/4885NOD1 1874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.