Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15122639 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL8671668 | 0.80 | MEN1 (0.60) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL6794925 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL6790960 | 0.78 | KMT2A (0.58) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL5376333 | 0.78 | MAPT (0.63) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL29900461 | 0.77 | MEN1 (0.60) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL19332390 | 0.77 | MEN1 (0.60) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL5657358 | 0.74 | MAPT (0.63) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL5380400 | 0.74 | MAPT (0.49) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL13722496 | 0.74 | MEN1 (0.60) | ALDH1A1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250136619-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. | 2025-05-01 | — | — | US | disclosed |
| WO-2024217557-A1 | SUBSTITUTED TETRAHYDROFURANS AS NAV1.8 INHIBITORS | 武汉人福创新药物研发中心有限公司 | 2024-10-24 | — | — | WO | disclosed |
| CN-118812519-A | Substituted tetrahydrofurans as Nav1.8 inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-10-22 | — | — | CN | disclosed |
| WO-2023059581-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2023-04-13 | — | — | WO | disclosed |
| CN-114391012-A | Pyridine derivatives as KIF18A inhibitors | 美国安进公司 | 2022-04-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250136619-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | CDK9, AURKB, AURKC | ALDH1A1 4464/4885MAPT 912/4885LMNA 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.