Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL262794 | 1.00 | HTR7 (0.61) | HTR7MAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL2896629 | 0.94 | MAPT (0.63) | HTR7MAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL268119 | 0.90 | MAPT (0.61) | HTR7MAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL10798879 | 0.89 | HTR7 (0.67) | HTR7MAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL31681465 | 0.85 | MAPT (0.50) | HTR7MAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL2974587 | 0.84 | MAPT (0.56) | MAPTL3MBTL1RAB9ANPC1CYP1A2 | |
| SCHEMBL15286819 | 0.82 | MAPT (0.44) | HTR7MAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL2344935 | 0.82 | HTR7 (0.64) | HTR7MAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL701534 | 0.82 | HTR7 (0.64) | HTR7MAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL755670 | 0.81 | HTR7 (0.53) | HTR7MAPTL3MBTL1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019388-A | 5-And 6-azaindole compounds for inhibiting Bcr-Abl tyrosine kinase | 英莱汶公司 | 2024-11-26 | — | — | CN | disclosed |
| EP-4225742-A1 | 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES | Enliven Therapeutics, Inc. (US) | 2023-08-16 | — | — | EP | disclosed |
| CN-114874251-A | Silicon center chiral silanol and synthetic method thereof | 南方科技大学 | 2022-08-09 | — | — | CN | disclosed |
| WO-2022076975-A1 | 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES | ENLIVEN THERAPEUTICS, INC. (US) | 2022-04-14 | — | — | WO | disclosed |