Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2344935 | 0.95 | HTR7 (0.64) | HTR7RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL30883281 | 0.93 | HTR7 (0.62) | HTR7RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL10798879 | 0.92 | HTR7 (0.67) | HTR7RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL268119 | 0.89 | MAPT (0.61) | HTR7RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL5661298 | 0.89 | HTR7 (0.58) | HTR7RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL29982369 | 0.89 | HTR7 (0.58) | HTR7RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL4213692 | 0.89 | HTR7 (0.58) | HTR7RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL23630252 | 0.87 | HTR7 (0.56) | HTR7RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL10367492 | 0.87 | HTR7 (0.56) | HTR7RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL4185846 | 0.87 | HTR7 (0.61) | HTR7RAB9ANPC1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10654029-B2 | Bridged bi-aromatic ligands and olefin polymerization catalysts prepared therefrom | UNIVATION TECHNOLOGIES, LLC (US) | 2020-05-19 | — | — | US | disclosed |
| EP-3285923-B1 | BRIDGED BI-AROMATIC LIGANDS AND OLEFIN POLYMERIZATION CATALYSTS PREPARED THEREFROM | UNIVATION TECH LLC (US) | 2019-07-17 | — | — | EP | disclosed |
| US-20190111414-A1 | BRIDGED BI-AROMATIC LIGANDS AND OLEFIN POLYMERIZATION CATALYSTS PREPARED THEREFROM | UNIVATION TECHNOLOGIES, LLC (US) | 2019-04-18 | — | — | US | disclosed |
| US-10195589-B2 | Bridged bi-aromatic ligands and olefin polymerization catalysts prepared therefrom | UNIVATION TECHNOLOGIES, LLC (US) | 2019-02-05 | — | — | US | disclosed |
| EP-3351250-A2 | PHOSPHATE MANAGEMENT WITH SMALL MOLECULES | Opko Ireland Global Holdings, Ltd. (IE) | 2018-07-25 | — | — | EP | disclosed |
| US-20180147562-A1 | BRIDGED BI-AROMATIC LIGANDS AND OLEFIN POLYMERIZATION CATALYSTS PREPARED THEREFROM | UNIVATION TECHNOLOGIES, LLC (US) | 2018-05-31 | — | — | US | disclosed |
| EP-3285923-A1 | BRIDGED BI-AROMATIC LIGANDS AND OLEFIN POLYMERIZATION CATALYSTS PREPARED THEREFROM | Univation Technologies, LLC (US) | 2018-02-28 | — | — | EP | disclosed |
| EP-3251677-A2 | PHOSPHATE MANAGEMENT WITH SMALL MOLECULES | OPKO Ireland Global Holdings, Limited (IE) | 2017-12-06 | — | — | EP | disclosed |
| EP-2389183-B1 | PHOSPHATE MANAGEMENT WITH SMALL MOLECULES | OPKO IRELAND GLOBAL HOLDINGS LTD (IE) | 2017-05-31 | — | — | EP | disclosed |
| WO-2016172097-A1 | BRIDGED BI-AROMATIC LIGANDS AND OLEFIN POLYMERIZATION CATALYSTS PREPARED THEREFROM | UNIVATION TECHNOLOGIES, LLC (US) | 2016-10-27 | — | — | WO | disclosed |
| US-7659415-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX SOLUTIONS, INC. (US) | 2010-02-09 | — | — | US | disclosed |
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-17 | — | — | US | disclosed |
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-17 | — | — | US | disclosed |
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-17 | — | — | US | disclosed |
| EP-1859005-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2007-11-28 | — | — | EP | disclosed |
| US-7241715-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241715-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| WO-2006097208-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2006-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | WEE1, WASF2, WEE2 | HTR7 935/4885RAB9A 4876/4885NPC1 4831/4885 |
| US-10654029-B2 | Bridged bi-aromatic ligands and olefin polymerization catalysts prepared therefrom | WASF2, WEE2, PICALM | HTR7 792/4885RAB9A 4536/4885NPC1 4377/4885 |
| US-10195589-B2 | Bridged bi-aromatic ligands and olefin polymerization catalysts prepared therefrom | WASF2, WEE2, PICALM | HTR7 792/4885RAB9A 4536/4885NPC1 4377/4885 |
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | OR10J3, EML4, TYR | HTR7 2564/4885RAB9A 2309/4885NPC1 4266/4885 |
| US-20190111414-A1 | BRIDGED BI-AROMATIC LIGANDS AND OLEFIN POLYMERIZATION CATALYSTS PREPARED THEREFROM | WASF2, WEE2, PICALM | HTR7 792/4885RAB9A 4536/4885NPC1 4377/4885 |
| US-20180147562-A1 | BRIDGED BI-AROMATIC LIGANDS AND OLEFIN POLYMERIZATION CATALYSTS PREPARED THEREFROM | WASF2, WEE2, PICALM | HTR7 792/4885RAB9A 4536/4885NPC1 4377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.