Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29778131 | 0.78 | PLA2G10 (0.43) | GPR84PLA2G10PLA2G2APLA2G5 | |
| SCHEMBL30565766 | 0.77 | CACNA2D1 (0.39) | — | |
| SCHEMBL30637506 | 0.75 | CACNA2D1 (0.33) | — | |
| SCHEMBL31003023 | 0.73 | CACNA2D1 (0.41) | — | |
| SCHEMBL30442889 | 0.72 | CACNA2D1 (0.44) | — | |
| SCHEMBL2695428 | 0.72 | CACNA2D1 (0.44) | — | |
| SCHEMBL31692789 | 0.72 | CACNA2D1 (0.40) | — | |
| SCHEMBL29885722 | 0.71 | CACNA2D1 (0.42) | — | |
| 3-Methylbutanoic Acid SCHEMBL627178 | 0.70 | GPR84 (0.56) | GPR84 | |
| SCHEMBL11909491 | 0.70 | CACNA2D1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114391012-A | Pyridine derivatives as KIF18A inhibitors | 美国安进公司 | 2022-04-22 | — | — | CN | disclosed |