Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 3/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31692789 | 0.82 | CACNA2D1 (0.40) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL29534823 | 0.78 | GPR84 (0.38) | PLA2G10GPR84PLA2G2APLA2G5 | |
| SCHEMBL2695428 | 0.76 | CACNA2D1 (0.44) | ALDH1A1CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL30442889 | 0.76 | CACNA2D1 (0.44) | ALDH1A1CACNA2D1CACNB3CACNA1CPGR | |
| SCHEMBL8973063 | 0.74 | GPR84 (0.46) | PLA2G10GPR84EPHX1KDM4EALDH1A1 | |
| SCHEMBL29885722 | 0.74 | CACNA2D1 (0.42) | ALDH1A1CACNA2D1CACNB3CACNA1CPGR | |
| 3-Methylbutanoic Acid SCHEMBL627178 | 0.73 | GPR84 (0.56) | GPR84ALDH1A1 | |
| SCHEMBL25244991 | 0.73 | GPR84 (0.48) | PLA2G10GPR84EPHX1ALDH1A1 | |
| SCHEMBL1248366 | 0.73 | GPR84 (0.48) | PLA2G10GPR84EPHX1ALDH1A1 | |
| SCHEMBL18159303 | 0.73 | GPR84 (0.48) | PLA2G10GPR84EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108064283-B | Binding triggered transcription switches and methods of use thereof | 加利福尼亚大学董事会 | 2024-01-09 | — | — | CN | disclosed |
| CN-115449529-A | Process for preparing ACC inhibitors and solid forms thereof | 吉利德科学公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-110382503-B | Process for preparing ACC inhibitors and solid forms thereof | 吉利德科学公司 | 2022-07-19 | — | — | CN | disclosed |