Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL799309 | 0.84 | PSMB5 (0.41) | LCKKDRJAK3MAPK14 | |
| SCHEMBL6844988 | 0.76 | BACE1 (0.46) | LCKKDRJAK3MAPK14 | |
| SCHEMBL8404380 | 0.75 | CYP1A2 (0.52) | — | |
| SCHEMBL12810119 | 0.75 | BRAF (0.40) | LCKKDRJAK3MAPK14 | |
| SCHEMBL3481303 | 0.72 | KDM4E (0.55) | LCKKDRJAK3MAPK14MAOA | |
| SCHEMBL31155594 | 0.72 | KDM4E (0.55) | LCKKDRJAK3MAPK14MAOA | |
| SCHEMBL15888390 | 0.72 | HTR3A (0.51) | LCKKDR | |
| SCHEMBL4539180 | 0.72 | NOS1 (0.37) | LCKKDRJAK3MAPK14MAOA | |
| SCHEMBL31391518 | 0.72 | BACE1 (0.46) | — | |
| SCHEMBL31731092 | 0.72 | MAPT (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995588-B | Synthesis method of 6- (dibromomethyl) -2-methyl quinazoline-4 (3H) -ketone | 宏冠生物药业有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-111995588-B | Synthesis method of 6- (dibromomethyl) -2-methyl quinazoline-4 (3H) -ketone | 宏冠生物药业有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-111995588-B | Synthesis method of 6- (dibromomethyl) -2-methyl quinazoline-4 (3H) -ketone | 宏冠生物药业有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-111995588-B | Synthesis method of 6- (dibromomethyl) -2-methyl quinazoline-4 (3H) -ketone | 宏冠生物药业有限公司 | 2022-04-22 | — | — | CN | disclosed |