SCHEMBL29535341

SCHEMBL29535341

O=C1CCC(Nc2ccc(N3CCNCC3)c(F)c2)C(=O)N1

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 20/20 0.67
CRBN Q96SW2 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25224278 1.00 DDB1 (0.67) DDB1CRBN
SCHEMBL25229880 1.00 DDB1 (0.67) DDB1CRBN
SCHEMBL30981342 1.00 DDB1 (0.67) DDB1CRBN
SCHEMBL25024305 1.00 DDB1 (0.67) DDB1CRBN
SCHEMBL30981547 1.00 DDB1 (0.67) DDB1CRBN
Hydrochloric Acid SCHEMBL25271450 0.99 DDB1 (0.66) DDB1CRBN
Hydrochloric Acid SCHEMBL29535772 0.99 DDB1 (0.66) DDB1CRBN
SCHEMBL31639297 0.96 DDB1 (0.62) DDB1CRBN
SCHEMBL23783368 0.92 DDB1 (0.57) DDB1CRBN
Trifluoroacetic Acid SCHEMBL29094651 0.92 DDB1 (0.58) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122029163-A Chemical for targeting chromatin remodeling complexes and uses thereof 丹娜-法伯癌症研究院 2026-05-12 CN disclosed
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
EP-4640686-A1 DEGRADER FOR DEGRADING BRD PROTEIN AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Innocure Therapeutics, Inc. (KR) 2025-10-29 EP disclosed
EP-4624472-A1 DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME Innocure Therapeutics, Inc. (KR) 2025-10-01 EP disclosed
EP-4624466-A1 DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Innocure Therapeutics, Inc. (KR) 2025-10-01 EP disclosed
EP-4587446-A1 BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2025-07-23 EP disclosed
WO-2025137605-A1 COMPOUNDS FOR TARGETED DEGRADATION OF PROTO-ONCOGENE TYROSINE PROTEIN KINASE RECEPTOR C4 THERAPEUTICS, INC. (US) 2025-06-26 WO disclosed
EP-4561999-A1 TARGETED PROTEIN DEGRADATION OF PARP14 FOR USE IN THERAPY Abbvie Operations Singapore Pte. Ltd. (SG) 2025-06-04 EP disclosed
EP-4562007-A1 TARGETED PROTEIN DEGRADATION OF PARP14 FOR USE IN THERAPY Abbvie Operations Singapore Pte. Ltd. (SG) 2025-06-04 EP disclosed
US-20250171417-A1 HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) 2025-05-29 US disclosed
WO-2024233846-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN LARKSPUR BIOSCIENCES, INC. (US) 2024-11-14 WO disclosed
EP-4392420-A1 HPK1 DEGRADERS, COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME BIOFRONT LTD (KY) 2024-07-03 EP disclosed
CN-117858874-A HPK1 degrading agents, compositions comprising the same, and methods of use thereof 百放开曼有限公司 2024-04-09 CN disclosed
WO-2024055112-A1 BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2024-03-21 WO disclosed
WO-2024026081-A1 TARGETED PROTEIN DEGRADATION OF PARP14 FOR USE IN THERAPY RIBON THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
WO-2024026083-A1 TARGETED PROTEIN DEGRADATION OF PARP14 FOR USE IN THERAPY RIBON THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
WO-2023193085-A1 BIFUNCTIONAL COMPOUNDS AND PHARMACEUTICAL USES THEREOF RISEN (SUZHOU) PHARMA TECH Co.,Ltd. (CN) 2023-10-12 WO disclosed
EP-4192458-A1 COMPOUNDS FOR TARGETED DEGRADATION OF RET C4 Therapeutics, Inc. (US) 2023-06-14 EP disclosed
WO-2023025091-A1 HPK1 DEGRADERS, COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME BIOFRONT LTD (CAYMAN) (KY) 2023-03-02 WO disclosed
WO-2022032026-A1 COMPOUNDS FOR TARGETED DEGRADATION OF RET C4 THERAPEUTICS, INC. (US) 2022-02-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171417-A1 HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF AR, BCKDK, CYP11B2 DDB1 3670/4885CRBN 2599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.