Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF1 | P05230 | 4/20 | 0.42 |
| ▸ | FGF2 | P09038 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | SERPINC1 | P01008 | 1/20 | 0.33 |
| ▸ | CXCL10 | P02778 | 1/20 | 0.32 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.32 |
| ▸ | CCL2 | P13500 | 1/20 | 0.32 |
| ▸ | CCL5 | P13501 | 1/20 | 0.32 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29535318 | 1.00 | FGF1 (0.42) | FGF1FGF2CA2F10SERPINC1 | |
| SCHEMBL29535174 | 0.88 | FGF1 (0.45) | FGF1FGF2CA2F10SERPINC1 | |
| SCHEMBL29535822 | 0.88 | FGF1 (0.45) | FGF1FGF2CA2F10SERPINC1 | |
| SCHEMBL8781311 | 0.86 | FGF1 (0.42) | FGF1FGF2CA2F10SERPINC1 | |
| SCHEMBL8781293 | 0.86 | FGF1 (0.42) | FGF1FGF2CA2F10SERPINC1 | |
| SCHEMBL9106001 | 0.86 | FGF1 (0.42) | FGF1FGF2CA2F10SERPINC1 | |
| SCHEMBL5178539 | 0.86 | FGF1 (0.42) | FGF1FGF2CA2F10SERPINC1 | |
| SCHEMBL29535305 | 0.84 | MAPT (0.39) | FGF1CA2CXCL10CXCL8CCL2 | |
| SCHEMBL19667936 | 0.84 | MAPT (0.39) | FGF1CA2CXCL10CXCL8CCL2 | |
| SCHEMBL5523032 | 0.84 | MAPT (0.39) | FGF1CA2CXCL10CXCL8CCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240366853-A1 | METHOD FOR MODULATING ENDOTHELIAL GLYCOCALYX STRUCTURE | EXTHERA MEDICAL CORPORATION (US) | 2024-11-07 | — | — | US | disclosed |
| US-12090261-B2 | Method for modulating endothelial glycocalyx structure | EXTHERA MEDICAL CORPORATION (US) | 2024-09-17 | — | — | US | disclosed |
| EP-3969014-A1 | METHOD FOR MODULATING ENDOTHELIAL GLYCOCALYX STRUCTURE | ExThera Medical Corporation (US) | 2022-03-23 | — | — | EP | disclosed |