Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 7/20 | 0.37 |
| ▸ | CA12 | O43570 | 6/20 | 0.37 |
| ▸ | CA9 | Q16790 | 6/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CXCL10 | P02778 | 1/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.33 |
| ▸ | CCL2 | P13500 | 1/20 | 0.33 |
| ▸ | CCL5 | P13501 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
| ▸ | FGF1 | P05230 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29535305 | 1.00 | MAPT (0.39) | MAPTGAALGALS3CA2CA12 | |
| SCHEMBL19667936 | 1.00 | MAPT (0.39) | MAPTGAALGALS3CA2CA12 | |
| SCHEMBL29535262 | 0.89 | BLM (0.35) | MAPTGAALGALS3CA2CA12 | |
| SCHEMBL29535395 | 0.89 | BLM (0.35) | MAPTGAALGALS3CA2CA12 | |
| SCHEMBL21753793 | 0.87 | BLM (0.37) | MAPTGAALGALS3CA2CA12 | |
| SCHEMBL29535705 | 0.87 | BLM (0.37) | MAPTGAALGALS3CA2CA12 | |
| SCHEMBL741519 | 0.86 | SLC2A1 (0.42) | MAPTLGALS3CA2CA12CA9 | |
| SCHEMBL150778 | 0.86 | SLC2A1 (0.42) | MAPTLGALS3CA2CA12CA9 | |
| SCHEMBL5318200 | 0.86 | SLC2A1 (0.42) | MAPTLGALS3CA2CA12CA9 | |
| SCHEMBL4294762 | 0.86 | MAPT (0.43) | MAPTGAALGALS3CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070042030-A1 | Preparation for the application of agents in mini-droplets | IDEA AG (DE) | 2007-02-22 | — | — | US | disclosed |
| US-6329531-B1 | FOR THERAPY OF ALZHEIMER'S DISEASE | SCHERING AG (DE) | 2001-12-11 | — | — | US | disclosed |
| US-6165500-A | Preparation for the application of agents in mini-droplets | IDEA AG (DE) | 2000-12-26 | — | — | US | disclosed |
| EP-0942756-A2 | OPTICAL DIAGNOSTIC AGENTS FOR DIAGNOSIS OF NEURODEGENERATIVE DISEASES BY MEANS OF NEAR INFRA-RED RADIATION (NIR RADIATION) | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998022146-A2 | OPTICAL DIAGNOSTIC AGENTS FOR DIAGNOSIS OF NEURODEGENERATIVE DISEASES BY MEANS OF NEAR INFRA-RED RADIATION (NIR RADIATION) | Institut für Diagnostikforschung GmbH an der Freien Universität Berlin (DE) | 1998-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070042030-A1 | Preparation for the application of agents in mini-droplets | FABP4, NPC1L1, LIPA | MAPT 3617/4885GAA 702/4885LGALS3 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.