Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CXCL10 | P02778 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | CCL2 | P13500 | 1/20 | 0.36 |
| ▸ | CCL5 | P13501 | 1/20 | 0.36 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FGF1 | P05230 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753793 | 1.00 | BLM (0.37) | BLMRECQLTDP1MAPTCXCL10 | |
| SCHEMBL29535262 | 0.89 | BLM (0.35) | BLMRECQLTDP1MAPTCXCL10 | |
| SCHEMBL29535395 | 0.89 | BLM (0.35) | BLMRECQLTDP1MAPTCXCL10 | |
| SCHEMBL5523032 | 0.87 | MAPT (0.39) | BLMRECQLTDP1MAPTCXCL10 | |
| SCHEMBL19667936 | 0.87 | MAPT (0.39) | BLMRECQLTDP1MAPTCXCL10 | |
| SCHEMBL29535305 | 0.87 | MAPT (0.39) | BLMRECQLTDP1MAPTCXCL10 | |
| SCHEMBL28201089 | 0.86 | LGALS3 (0.38) | BLMCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL3914085 | 0.86 | LGALS3 (0.38) | BLMCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL2186684 | 0.86 | LGALS3 (0.38) | BLMCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL870879 | 0.86 | LGALS3 (0.38) | BLMCXCL10CXCL8CCL2CCL5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240366853-A1 | METHOD FOR MODULATING ENDOTHELIAL GLYCOCALYX STRUCTURE | EXTHERA MEDICAL CORPORATION (US) | 2024-11-07 | — | — | US | disclosed |
| US-12090261-B2 | Method for modulating endothelial glycocalyx structure | EXTHERA MEDICAL CORPORATION (US) | 2024-09-17 | — | — | US | disclosed |
| EP-3969014-A1 | METHOD FOR MODULATING ENDOTHELIAL GLYCOCALYX STRUCTURE | ExThera Medical Corporation (US) | 2022-03-23 | — | — | EP | disclosed |