Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | PI4KA | P42356 | 2/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155941 | 0.67 | KDR (0.32) | NUDT1 | |
| Adenine SCHEMBL5543734 | 0.67 | PI4KA (0.42) | BLMPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL5989622 | 0.66 | ADORA2A (0.41) | ADORA2AADORA1BLMKDM4EALDH1A1 | |
| SCHEMBL1057968 | 0.65 | ALDH1A1 (0.43) | NUDT1BLMKDM4EALDH1A1DHFR | |
| 2,6-Diaminopurine SCHEMBL2316818 | 0.65 | KDM4E (0.32) | NUDT1BLMKDM4EALDH1A1CYP3A4 | |
| SCHEMBL1800839 | 0.64 | CDK5 (0.42) | NUDT1BLMPI4KBKDM4EALDH1A1 | |
| 6-Chloroguanine SCHEMBL3268234 | 0.63 | MMP12 (0.33) | NUDT1 | |
| SCHEMBL42313 | 0.62 | ADORA2A (0.42) | NUDT1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL42314 | 0.61 | ADORA2A (0.66) | NUDT1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL29400753 | 0.61 | ADORA2A (0.66) | NUDT1ADORA2AADORA1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |