Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDR | P35968 | 3/20 | 0.49 |
| ▸ | CSF1R | P07333 | 2/20 | 0.49 |
| ▸ | KIT | P10721 | 2/20 | 0.49 |
| ▸ | LCK | P06239 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | LYN | P07948 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | BLK | P51451 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3187182 | 1.00 | MEN1 (0.56) | MEN1KMT2AKDRCSF1RKIT | |
| SCHEMBL23500689 | 0.87 | GAA (0.54) | MEN1KMT2AKDRKITFLT3 | |
| SCHEMBL19263436 | 0.85 | KMT2A (0.56) | MEN1KMT2ACSF1RFLT3SMN1; SMN2 | |
| SCHEMBL3188022 | 0.80 | MEN1 (0.50) | MEN1KMT2AKDRCSF1RKIT | |
| SCHEMBL27983617 | 0.80 | KMT2A (0.56) | MEN1KMT2AKDRCSF1RKIT | |
| SCHEMBL29536398 | 0.79 | AKT1 (0.44) | KDRFLT1FLT4FLT3RAB9A | |
| Hydrochloric Acid SCHEMBL29536731 | 0.78 | KMT2A (0.57) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL29536538 | 0.78 | POLB (0.47) | KMT2AKDRKITFLT3SMN1; SMN2 | |
| SCHEMBL23501077 | 0.78 | POLB (0.47) | KMT2AKDRKITFLT3SMN1; SMN2 | |
| SCHEMBL4291228 | 0.77 | NPC1 (0.56) | MEN1KMT2AKDRCSF1RKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112939948-B | Novel quinazoline-containing compound, intermediate and application thereof | 苏州美诺医药科技有限公司 | 2022-05-17 | — | — | CN | disclosed |