Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 4/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 6/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25226268 | 1.00 | MAPK8 (0.45) | MAPK8MAPK14TRPA1METMAPT | |
| SCHEMBL16650398 | 0.86 | TRPA1 (0.42) | MAPK14TRPA1METMAPTRXFP1 | |
| SCHEMBL14014291 | 0.86 | MAPK8 (0.45) | MAPK8MAPK14TRPA1MET | |
| SCHEMBL5122174 | 0.79 | MAPK8 (0.43) | MAPK8MAPK14MET | |
| SCHEMBL29536776 | 0.79 | MAPK8 (0.42) | MAPK8MAPK14MET | |
| SCHEMBL25222319 | 0.79 | MAPK8 (0.42) | MAPK8MAPK14MET | |
| SCHEMBL25043087 | 0.77 | TRPA1 (0.43) | MAPK14TRPA1MET | |
| SCHEMBL16650836 | 0.76 | MET (0.44) | MAPK8MAPK14TRPA1METMAPT | |
| SCHEMBL6073354 | 0.76 | MEN1 (0.38) | MAPTRXFP1 | |
| SCHEMBL5111814 | 0.76 | FGFR1 (0.46) | MAPK8MAPK14MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710453-A | Kinase inhibitors and uses thereof | 璧辰医药技术股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| EP-4192582-A1 | KINASE INHIBITORS AND USES THEREOF | ABM Therapeutics Corporation (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032071-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORPORATION (US) | 2022-02-10 | — | — | WO | disclosed |