Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 7/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 5/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | PAICS | P22234 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 5/20 | 0.32 |
| ▸ | CDK4 | P11802 | 3/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24285931 | 1.00 | JAK1 (0.34) | JAK1PRKCAPRKCIPRKCEROCK2 | |
| SCHEMBL24285989 | 0.93 | CDK2 (0.34) | JAK1PRKCAPRKCIPRKCEJAK2 | |
| SCHEMBL29537364 | 0.93 | CDK2 (0.34) | JAK1PRKCAPRKCIPRKCEJAK2 | |
| SCHEMBL29537535 | 0.90 | JAK1 (0.36) | JAK1PRKCAPRKCIPRKCEJAK2 | |
| SCHEMBL24285879 | 0.90 | JAK1 (0.36) | JAK1PRKCAPRKCIPRKCEJAK2 | |
| SCHEMBL24285860 | 0.84 | ABL1 (0.41) | — | |
| SCHEMBL29538200 | 0.84 | LRRK2 (0.45) | ROCK2JAK2CDK2PAK4CCNC | |
| SCHEMBL24285969 | 0.84 | LRRK2 (0.45) | ROCK2JAK2CDK2PAK4CCNC | |
| SCHEMBL24285965 | 0.83 | PRKCA (0.35) | JAK1PRKCAPRKCIPRKCEJAK2 | |
| SCHEMBL29537655 | 0.83 | PRKCA (0.35) | JAK1PRKCAPRKCIPRKCEJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214207-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1st Biotherapeutics, Inc. (KR) | 2023-07-26 | — | — | EP | claimed |
| CN-116457355-A | 2-amino-3-carbonyl imidazopyridines and pyrazolopyridines compounds | 第一生物治疗股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| WO-2022058890-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1ST Biotherapeutics, Inc. (KR) | 2022-03-24 | — | — | WO | claimed |