Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 4/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 6/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CCNH | P51946 | 1/20 | 0.41 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24285858 | 1.00 | RIPK1 (0.44) | RIPK1PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL24285867 | 0.88 | RIPK1 (0.45) | RIPK1PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL29537513 | 0.88 | RIPK1 (0.45) | RIPK1PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL29537181 | 0.85 | RIPK1 (0.47) | RIPK1PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL24285984 | 0.85 | RIPK1 (0.47) | RIPK1PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL24286063 | 0.82 | CDK2 (0.35) | PIK3CACDK8CCNCCDK2CSNK1D | |
| SCHEMBL29537492 | 0.82 | CDK2 (0.35) | PIK3CACDK8CCNCCDK2CSNK1D | |
| SCHEMBL24285848 | 0.77 | LRRK2 (0.47) | RIPK1PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL29537003 | 0.77 | LRRK2 (0.47) | RIPK1PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL24285977 | 0.77 | LRRK2 (0.59) | RIPK1PIK3CAPIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214207-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1st Biotherapeutics, Inc. (KR) | 2023-07-26 | — | — | EP | claimed |
| CN-116457355-A | 2-amino-3-carbonyl imidazopyridines and pyrazolopyridines compounds | 第一生物治疗股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| WO-2022058890-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1ST Biotherapeutics, Inc. (KR) | 2022-03-24 | — | — | WO | claimed |