Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.46 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 6/20 | 0.42 |
| ▸ | CDK7 | P50613 | 2/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | CCNH | P51946 | 1/20 | 0.42 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | ROS1 | P08922 | 2/20 | 0.40 |
| ▸ | MARK3 | P27448 | 2/20 | 0.40 |
| ▸ | FLT4 | P35916 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | CLK2 | P49760 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24285848 | 1.00 | LRRK2 (0.47) | LRRK2RIPK1MAP4K1CDK8CDK7 | |
| SCHEMBL24285969 | 0.94 | LRRK2 (0.45) | LRRK2RIPK1MAP4K1CDK8CDK7 | |
| SCHEMBL29538200 | 0.94 | LRRK2 (0.45) | LRRK2RIPK1MAP4K1CDK8CDK7 | |
| SCHEMBL29537401 | 0.86 | LRRK2 (0.59) | LRRK2RIPK1MAP4K1CDK8CDK7 | |
| SCHEMBL24285977 | 0.86 | LRRK2 (0.59) | LRRK2RIPK1MAP4K1CDK8CDK7 | |
| SCHEMBL24285965 | 0.81 | PRKCA (0.35) | LRRK2ABL1JAK2 | |
| SCHEMBL29537655 | 0.81 | PRKCA (0.35) | LRRK2ABL1JAK2 | |
| SCHEMBL24285989 | 0.81 | CDK2 (0.34) | LRRK2CDK8CCNCABL1CDK2 | |
| SCHEMBL29537364 | 0.81 | CDK2 (0.34) | LRRK2CDK8CCNCABL1CDK2 | |
| SCHEMBL24285984 | 0.80 | RIPK1 (0.47) | LRRK2RIPK1MAP4K1CDK8CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214207-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1st Biotherapeutics, Inc. (KR) | 2023-07-26 | — | — | EP | claimed |
| CN-116457355-A | 2-amino-3-carbonyl imidazopyridines and pyrazolopyridines compounds | 第一生物治疗股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| WO-2022058890-A1 | 2-AMINO-3-CARBONYL IMIDAZOPYRIDINE AND PYRAZOLOPYRIDINE COMPOUNDS | 1ST Biotherapeutics, Inc. (KR) | 2022-03-24 | — | — | WO | claimed |