Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 2/20 | 0.58 |
| ▸ | ACACB | O00763 | 1/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 11/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14935921 | 1.00 | ACACA (0.58) | ACACAACACBADORA2BMEN1KMT2A | |
| SCHEMBL14936770 | 0.93 | ACACA (0.60) | ACACAACACBADORA2BMEN1KMT2A | |
| SCHEMBL29538237 | 0.93 | ACACA (0.60) | ACACAACACBADORA2BMEN1KMT2A | |
| SCHEMBL16920244 | 0.92 | ACACA (0.59) | ACACAACACBADORA2BMEN1KMT2A | |
| SCHEMBL29538158 | 0.90 | ADORA2B (0.57) | ACACAACACBADORA2BMEN1KMT2A | |
| SCHEMBL14936574 | 0.90 | ADORA2B (0.57) | ACACAACACBADORA2BMEN1KMT2A | |
| SCHEMBL14935930 | 0.89 | ACACB (0.73) | ACACAACACBADORA2BMEN1KMT2A | |
| SCHEMBL20220649 | 0.88 | ACACA (0.55) | ACACAACACBADORA2BMEN1KMT2A | |
| SCHEMBL14936094 | 0.87 | ACACA (0.54) | ACACAACACBADORA2BMEN1KMT2A | |
| SCHEMBL29538550 | 0.87 | ACACA (0.54) | ACACAACACBADORA2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970760-B | ACC inhibitors and uses thereof | 吉利德阿波罗公司 | 2022-04-26 | — | — | CN | disclosed |