SCHEMBL29538219

SCHEMBL29538219

Nc1cc2c(cc1F)OCC=N2

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SYK P43405 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30684782 1.00 SYK (0.39) SYK
SCHEMBL30664492 0.79 BACE1 (0.34) SYK
SCHEMBL30748266 0.72 ATM (0.38) —
SCHEMBL657838 0.72 MAPT (0.40) SYK
SCHEMBL30748267 0.70 SYK (0.33) SYK
SCHEMBL30671626 0.70 MAPT (0.39) SYK
SCHEMBL657497 0.70 MAPT (0.39) SYK
SCHEMBL30513578 0.67 SYK (0.45) SYK
SCHEMBL6374125 0.67 ENPP2 (0.31) —
SCHEMBL5166376 0.67 SYK (0.45) SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462550-A Preparation method of 6-amino-7-fluoro-2H-1, 4-benzoxazine-3- (4H) ketone 山东京博农化科技股份有限公司 2025-02-18 — — CN claimed
CN-118290359-A Preparation method of 6-amino-7-fluoro-4-propynyl-1, 4-benzoxazine-3- (4H) ketone 山东京博农化科技股份有限公司 2024-07-05 — — CN claimed
CN-117164576-A Synthesis method of flumioxazin 上海农帆生物科技有限公司 2023-12-05 — — CN claimed
CN-113912561-B Synthetic method of 6-amino-7-fluoro-2H-1, 4-benzoxazine-3 (4H) -ketone 山东京博农化科技股份有限公司 2023-04-07 — — CN claimed
CN-115466249-A Preparation method of flumioxazin 上海农帆生物科技有限公司 2022-12-13 — — CN claimed
CN-119462550-A Preparation method of 6-amino-7-fluoro-2H-1, 4-benzoxazine-3- (4H) ketone 山东京博农化科技股份有限公司 2025-02-18 — — CN disclosed
CN-119462550-A Preparation method of 6-amino-7-fluoro-2H-1, 4-benzoxazine-3- (4H) ketone 山东京博农化科技股份有限公司 2025-02-18 — — CN disclosed
CN-119462550-A Preparation method of 6-amino-7-fluoro-2H-1, 4-benzoxazine-3- (4H) ketone 山东京博农化科技股份有限公司 2025-02-18 — — CN disclosed
CN-119059987-A Flumioxazin Synthesis method of intermediate 利尔化学股份有限公司 2024-12-03 — — CN disclosed
CN-119059987-A Flumioxazin Synthesis method of intermediate 利尔化学股份有限公司 2024-12-03 — — CN disclosed
CN-118290359-A Preparation method of 6-amino-7-fluoro-4-propynyl-1, 4-benzoxazine-3- (4H) ketone 山东京博农化科技股份有限公司 2024-07-05 — — CN disclosed
CN-118290359-A Preparation method of 6-amino-7-fluoro-4-propynyl-1, 4-benzoxazine-3- (4H) ketone 山东京博农化科技股份有限公司 2024-07-05 — — CN disclosed
CN-117164576-A Synthesis method of flumioxazin 上海农帆生物科技有限公司 2023-12-05 — — CN disclosed
CN-113912561-B Synthetic method of 6-amino-7-fluoro-2H-1, 4-benzoxazine-3 (4H) -ketone 山东京博农化科技股份有限公司 2023-04-07 — — CN disclosed
CN-113912561-B Synthetic method of 6-amino-7-fluoro-2H-1, 4-benzoxazine-3 (4H) -ketone 山东京博农化科技股份有限公司 2023-04-07 — — CN disclosed
CN-113912561-B Synthetic method of 6-amino-7-fluoro-2H-1, 4-benzoxazine-3 (4H) -ketone 山东京博农化科技股份有限公司 2023-04-07 — — CN disclosed
CN-115466249-A Preparation method of flumioxazin 上海农帆生物科技有限公司 2022-12-13 — — CN disclosed
CN-115466249-A Preparation method of flumioxazin 上海农帆生物科技有限公司 2022-12-13 — — CN disclosed
CN-108976129-B Preparation method of 2- (5-fluoro-2, 4-dinitrophenoxy) acetate 安徽宁亿泰科技有限公司 2022-10-28 — — CN disclosed
CN-110240545-B Preparation method of 2- (5-fluoro-2, 4-dinitrophenoxy) acetic acid 迈克斯(如东)化工有限公司 2022-04-26 — — CN disclosed
Send feedback