Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 8/20 | 0.61 |
| ▸ | CCNB2 | O95067 | 7/20 | 0.61 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.61 |
| ▸ | CCNB3 | Q8WWL7 | 7/20 | 0.61 |
| ▸ | CDK2 | P24941 | 2/20 | 0.61 |
| ▸ | NT5E | P21589 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.48 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CCNH | P51946 | 1/20 | 0.46 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19100489 | 1.00 | CDK1 (0.61) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL21450235 | 0.85 | NT5E (0.54) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL22843545 | 0.83 | CDK1 (0.54) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL19370351 | 0.81 | NT5E (0.50) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL19100815 | 0.80 | RAB9A (0.57) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL21316709 | 0.80 | CDK1 (0.81) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL22843495 | 0.79 | CDK2 (0.49) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL21348733 | 0.78 | TMIGD3 (0.58) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL19370287 | 0.78 | CCNB2 (0.47) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL754120 | 0.77 | CDK1 (1.00) | CDK1CCNB2CCNB1CCNB3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912510-A | Modulators of extracellular 5' -nucleotidases and uses thereof | 艾库斯生物科学有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-114395005-B | Modulators of extracellular 5' -nucleotidases and uses thereof | 艾库斯生物科学有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-108697719-B | Modulators of extracellular 5' -nucleotidases and uses thereof | 艾库斯生物科学有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-114395005-A | Modulators of extracellular 5' -nucleotidase and uses thereof | 艾库斯生物科学有限公司 | 2022-04-26 | — | — | CN | disclosed |