Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.58 |
| ▸ | NT5E | P21589 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 2/20 | 0.51 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19100815 | 0.80 | RAB9A (0.57) | TMIGD3ADORA2AADORA1NT5ERAB9A | |
| SCHEMBL19100489 | 0.78 | CDK1 (0.61) | TMIGD3ADORA2AADORA1NT5ERAB9A | |
| SCHEMBL29539043 | 0.78 | CDK1 (0.61) | TMIGD3ADORA2AADORA1NT5ERAB9A | |
| SCHEMBL28068467 | 0.76 | TMIGD3 (0.77) | TMIGD3ADORA2AADORA1RAB9AKMT2A | |
| SCHEMBL27734468 | 0.74 | TMIGD3 (1.00) | TMIGD3ADORA2AADORA1RAB9AKMT2A | |
| SCHEMBL458946 | 0.74 | TMIGD3 (0.77) | TMIGD3ADORA2AADORA1RAB9AKMT2A | |
| SCHEMBL23431307 | 0.73 | NT5E (1.00) | NT5EDNPH1TDP1ENPP1 | |
| SCHEMBL29393691 | 0.73 | NT5E (1.00) | NT5EDNPH1TDP1ENPP1 | |
| SCHEMBL21450235 | 0.73 | NT5E (0.54) | TMIGD3ADORA2AADORA1NT5ERAB9A | |
| SCHEMBL27967736 | 0.73 | RAB9A (0.70) | TMIGD3ADORA2AADORA1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019173682-A1 | PARENTERALLY ADMINISTERED IMMUNE ENHANCING DRUGS | ARCUS BIOSCIENCES, INC. (US) | 2019-09-12 | — | — | WO | disclosed |