Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29538560 | 0.81 | MAPT (0.34) | ALDH1A1NPSR1MEN1MAPTBLM | |
| SCHEMBL22749197 | 0.72 | ALDH1A1 (0.40) | ALDH1A1LMNANPSR1PDE5APDE4B | |
| SCHEMBL22749220 | 0.65 | ALDH1A1 (0.36) | ALDH1A1LMNANPSR1MEN1GMNN | |
| SCHEMBL29538956 | 0.64 | ALDH1A1 (0.43) | ALDH1A1LMNANPSR1CYP1A2MAPT | |
| SCHEMBL22749207 | 0.62 | CNR2 (0.47) | ALDH1A1LMNACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL27718231 | 0.61 | MAPK1 (0.58) | ALDH1A1LMNAMEN1CYP1A2CYP3A4 | |
| Hexane SCHEMBL20638505 | 0.61 | ALDH1A1 (0.80) | ALDH1A1FAAHLMNATSHRSMN1; SMN2 | |
| SCHEMBL24929487 | 0.61 | ALDH1A1 (0.65) | ALDH1A1FAAHTSHR | |
| SCHEMBL30604754 | 0.61 | ALDH1A1 (0.65) | ALDH1A1FAAHTSHR | |
| Acetic Acid Butyl Ester SCHEMBL29163494 | 0.60 | ALDH1A1 (0.69) | ALDH1A1FAAHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12358919-B2 | Antibacterial compounds | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2025-07-15 | — | — | US | disclosed |
| US-20220235059-A1 | ANTIBACTERIAL COMPOUNDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2022-07-28 | — | — | US | disclosed |
| EP-3980418-A1 | ANTIBACTERIAL COMPOUNDS | Universita' Degli Studi di Siena (IT) | 2022-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12358919-B2 | Antibacterial compounds | ABCB11, CFTR, MRPL21 | ALDH1A1 931/4885FAAH 3208/4885LMNA 4093/4885 |
| US-20220235059-A1 | ANTIBACTERIAL COMPOUNDS | ABCB11, CFTR, MRPL21 | ALDH1A1 931/4885FAAH 3208/4885LMNA 4093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.