Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22209972 | 1.00 | TDP1 (0.40) | TDP1DRD2DRD4MEN1KMT2A | |
| SCHEMBL22194613 | 0.86 | TDP1 (0.39) | TDP1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL28725147 | 0.86 | TDP1 (0.39) | TDP1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL22194759 | 0.82 | SLC6A4 (0.41) | DRD2MEN1KMT2ADRD3 | |
| SCHEMBL22210144 | 0.82 | SLC6A4 (0.41) | DRD2MEN1KMT2ADRD3 | |
| SCHEMBL22194756 | 0.82 | SLC6A4 (0.41) | DRD2MEN1KMT2ADRD3 | |
| SCHEMBL28725131 | 0.77 | TMEM97 (0.38) | DRD2DRD4MEN1KMT2ATMEM97 | |
| SCHEMBL28725165 | 0.76 | SLC9A1 (0.42) | TDP1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL22209882 | 0.76 | SLC9A1 (0.42) | TDP1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL22209869 | 0.76 | DRD2 (0.42) | DRD2DRD4MEN1KMT2ATMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874209-B | Oxadiazole transient receptor potential channel inhibitors | 豪夫迈·罗氏有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-114874209-A | Oxadiazole transient receptor potential channel inhibitors | 豪夫迈·罗氏有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-110461838-B | Oxadiazole transient receptor potential channel inhibitors | 豪夫迈·罗氏有限公司 | 2022-05-06 | — | — | CN | disclosed |