Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 12/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.38 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28725141 | 1.00 | ATM (0.44) | ATMTRPA1ACACBCHI3L1KCNH2 | |
| SCHEMBL22194620 | 1.00 | ATM (0.44) | ATMTRPA1ACACBCHI3L1KCNH2 | |
| SCHEMBL22194619 | 1.00 | ATM (0.44) | ATMTRPA1ACACBCHI3L1KCNH2 | |
| SCHEMBL22194434 | 1.00 | ATM (0.44) | ATMTRPA1ACACBCHI3L1KCNH2 | |
| SCHEMBL22194400 | 0.82 | TRPA1 (0.39) | TRPA1CHI3L1CHIT1CHIADPP4 | |
| SCHEMBL22194403 | 0.82 | TRPA1 (0.39) | TRPA1CHI3L1CHIT1CHIADPP4 | |
| SCHEMBL22194401 | 0.82 | TRPA1 (0.39) | TRPA1CHI3L1CHIT1CHIADPP4 | |
| SCHEMBL22210091 | 0.76 | ACACB (0.41) | ATMTRPA1ACACBCHI3L1KCNH2 | |
| SCHEMBL30556697 | 0.76 | ATM (0.46) | ATMTRPA1ACACBCHI3L1KCNH2 | |
| SCHEMBL22194636 | 0.72 | HTR3E (0.46) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874209-B | Oxadiazole transient receptor potential channel inhibitors | 豪夫迈·罗氏有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-114874209-A | Oxadiazole transient receptor potential channel inhibitors | 豪夫迈·罗氏有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-110461838-B | Oxadiazole transient receptor potential channel inhibitors | 豪夫迈·罗氏有限公司 | 2022-05-06 | — | — | CN | disclosed |