SCHEMBL29540470

SCHEMBL29540470

Nc1cc(C(c2ccc(NCc3ccccc3)c(N)c2)(C(F)(F)F)C(F)(F)F)ccc1NCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
GFER P55789 1/20 0.47
KMT2A Q03164 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PTPN5 P54829 1/20 0.42
BACE1 P56817 1/20 0.41
HDAC6 Q9UBN7 1/20 0.40
APP P05067 4/20 0.39
HSD17B10 Q99714 1/20 0.39
IDO1 P14902 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
HDAC3 O15379 1/20 0.37
NCOR1 O75376 1/20 0.37
PTPN1 P18031 1/20 0.37
PTPRZ1 P23471 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL376685 1.00 KDM4E (0.47) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL18983680 0.88 ALDH1A1 (0.60) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL28238458 0.86 KDM4E (0.44) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL28238459 0.85 MEN1 (0.43) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL15311091 0.82 MAPT (0.44) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL29540627 0.78 MAPT (0.47) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL376030 0.78 MAPT (0.47) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL376200 0.77 GAA (0.77) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL29708495 0.77 GAA (0.77) KDM4EMEN1ALDH1A1GAAMAPT
SCHEMBL29540467 0.77 GAA (0.77) KDM4EMEN1ALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12275832-B2 Fluorine-containing elastomer composition and method for making cured fluorine-containing elastomer composition TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY LTD. (TW) 2025-04-15 US disclosed
US-20250026905-A1 COMPOSITION, CROSSLINKED ARTICLE AND SEALING MATERIAL DAIKIN INDUSTRIES, LTD. (JP) 2025-01-23 US disclosed
US-20240067796-A1 FLUORINE-CONTAINING ELASTOMER COMPOSITION AND METHOD FOR MAKING CURED FLUORINE-CONTAINING ELASTOMER COMPOSITION TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY LTD. (TW) 2024-02-29 US disclosed
WO-2023210818-A1 COMPOSITION INCLUDING FLUORORUBBER ダイキン工業株式会社 2023-11-02 WO disclosed
EP-4260348-A1 POLYMER AND ELASTOMER COMPOSITIONS HAVING CARBON NANOSTRUCTURE ADDITIVES AND ARTICLES FORMED THEREFROM FOR USE IN EMI AND RFI SHIELDING AND IN PRESSURE SENSING SEALS HAVING QUANTUM TUNNELING COMPOSITE EFFECTS Greene, Tweed Technologies, Inc. (US) 2023-10-18 EP disclosed
WO-2023195485-A1 COMPOSITION AND CROSSLINKED PRODUCT ダイキン工業株式会社 2023-10-12 WO disclosed
WO-2023189547-A1 COMPOSITION, CROSSLINKED PRODUCT, AND SEALING MATERIAL ダイキン工業株式会社 2023-10-05 WO disclosed
WO-2022125666-A9 POLYMER AND ELASTOMER COMPOSITIONS HAVING CARBON NANOSTRUCTURE ADDITIVES AND ARTICLES FORMED THEREFROM FOR USE IN EMI AND RFI SHIELDING AND IN PRESSURE SENSING SEALS HAVING QUANTUM TUNNELING COMPOSITE EFFECTS GREENE, TWEED TECHNOLOGIES, INC. (US) 2023-05-25 WO disclosed
WO-2022230706-A1 BISDIAMINOPHENYL COMPOUND, CROSSLINKING AGENT, COMPOSITION, AND MOLDED ARTICLE ダイキン工業株式会社 2022-11-03 WO disclosed
WO-2022125666-A1 POLYMER AND ELASTOMER COMPOSITIONS HAVING CARBON NANOSTRUCTURE ADDITIVES AND ARTICLES FORMED THEREFROM FOR USE IN EMI AND RFI SHIELDING AND IN PRESSURE SENSING SEALS HAVING QUANTUM TUNNELING COMPOSITE EFFECTS GREENE, TWEED TECHNOLOGIES, INC. (US) 2022-06-16 WO disclosed
WO-2022114012-A1 FLUOROPOLYMER, AQUEOUS LIQUID DISPERSION, COMPOSITION, AND CROSSLINKED PRODUCT ダイキン工業株式会社 2022-06-02 WO disclosed
WO-2022107890-A1 METHOD FOR MANUFACTURING PERFLUOROELASTOMER AQUEOUS DISPERSION, COMPOSITION, CROSSLINKABLE COMPOSITION, AND CROSSLINKED PRODUCT ダイキン工業株式会社 2022-05-27 WO disclosed
CN-109578581-B Seal comprising metal cover, method of making same, and method of using same 台湾积体电路制造股份有限公司 2022-03-25 CN disclosed