Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5849101 | 0.94 | TK1 (0.43) | TK1LMNATSHRALBPKM | |
| SCHEMBL2954292 | 0.88 | TK1 (0.38) | TK1 | |
| SCHEMBL1891880 | 0.85 | TK1 (0.40) | TK1LMNATSHRALBPKM | |
| SCHEMBL660497 | 0.81 | TK1 (0.45) | TK1LMNATSHRALBPKM | |
| SCHEMBL6832192 | 0.81 | TK1 (0.45) | TK1LMNATSHRALBPKM | |
| SCHEMBL29364921 | 0.81 | TK1 (0.45) | TK1LMNATSHRALBPKM | |
| SCHEMBL1517629 | 0.80 | TK1 (0.44) | TK1LMNATSHRALBPKM | |
| SCHEMBL16187026 | 0.80 | TK1 (0.44) | TK1LMNATSHRALBPKM | |
| SCHEMBL4809531 | 0.80 | TK1 (0.44) | TK1LMNATSHRALBPKM | |
| SCHEMBL135210 | 0.80 | TK1 (0.44) | TK1LMNATSHRALBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7749699-B2 | Detection of chemical ligation using fluorescence quenching leaving groups | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2010-07-06 | — | — | US | disclosed |
| EP-1543156-A4 | DETECTION OF CHEMICAL LIGATION USING FLUORESCENCE QUENCHING LEAVING GROUPS | UNIV LELAND STANFORD JUNIOR (US) | 2005-12-21 | — | — | EP | disclosed |
| EP-1543156-A2 | DETECTION OF CHEMICAL LIGATION USING FLUORESCENCE QUENCHING LEAVING GROUPS | The Board of Trustees of the Leland Stanford Junior University (US) | 2005-06-22 | — | — | EP | disclosed |
| US-20040259102-A1 | DETECTION OF CHEMICAL LIGATION USING FLUORESCENCE QUENCHING LEAVING GROUPS | STANFORD UNIVERSITY (US) | 2004-12-23 | — | — | US | disclosed |
| WO-2004010101-A2 | DETECTION OF CHEMICAL LIGATION USING FLUORESCENCE QUENCHING LEAVING GROUPS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2004-01-29 | — | — | WO | disclosed |