Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2954285 | 0.88 | TK1 (0.40) | TK1 | |
| SCHEMBL1891892 | 0.86 | TK1 (0.38) | TK1ALDH1A1NPSR1POLB | |
| SCHEMBL27835422 | 0.85 | TK1 (0.37) | TK1ALDH1A1NPSR1POLB | |
| SCHEMBL5849101 | 0.84 | TK1 (0.43) | TK1ALDH1A1POLB | |
| SCHEMBL7743997 | 0.80 | TK1 (0.37) | TK1 | |
| SCHEMBL1891880 | 0.73 | TK1 (0.40) | TK1ALDH1A1POLB | |
| SCHEMBL210837 | 0.72 | POLB (0.63) | TK1POLB | |
| SCHEMBL888124 | 0.71 | TK1 (0.37) | TK1ALDH1A1NPSR1POLB | |
| SCHEMBL660497 | 0.70 | TK1 (0.45) | TK1ALDH1A1POLB | |
| SCHEMBL31627956 | 0.70 | TK1 (0.43) | TK1ALDH1A1NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7749699-B2 | Detection of chemical ligation using fluorescence quenching leaving groups | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2010-07-06 | — | — | US | disclosed |
| EP-1543156-A4 | DETECTION OF CHEMICAL LIGATION USING FLUORESCENCE QUENCHING LEAVING GROUPS | UNIV LELAND STANFORD JUNIOR (US) | 2005-12-21 | — | — | EP | disclosed |
| EP-1543156-A2 | DETECTION OF CHEMICAL LIGATION USING FLUORESCENCE QUENCHING LEAVING GROUPS | The Board of Trustees of the Leland Stanford Junior University (US) | 2005-06-22 | — | — | EP | disclosed |
| US-20040259102-A1 | DETECTION OF CHEMICAL LIGATION USING FLUORESCENCE QUENCHING LEAVING GROUPS | STANFORD UNIVERSITY (US) | 2004-12-23 | — | — | US | disclosed |
| WO-2004010101-A2 | DETECTION OF CHEMICAL LIGATION USING FLUORESCENCE QUENCHING LEAVING GROUPS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2004-01-29 | — | — | WO | disclosed |