SCHEMBL29543716

SCHEMBL29543716

Cc1cc(=O)oc2cc(NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)ccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA9 Q16790 2/20 0.52
MAP1LC3B Q9GZQ8 1/20 0.46
MAP1LC3A Q9H492 1/20 0.46
KDM4E B2RXH2 4/20 0.44
ALDH1A1 P00352 4/20 0.44
HPGD P15428 4/20 0.44
RAB9A P51151 3/20 0.44
NPC1 O15118 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
HSD17B10 Q99714 2/20 0.43
TDP1 Q9NUW8 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
EGFR P00533 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1038137 1.00 CA12 (0.52) CA12CA1CA9MAP1LC3BMAP1LC3A
Acetic Acid SCHEMBL29692693 0.98 CA12 (0.50) CA12CA1CA9MAP1LC3BMAP1LC3A
SCHEMBL990344 0.89 KDM4E (0.57) CA12CA1CA9KDM4EALDH1A1
SCHEMBL14725053 0.89 CA12 (0.64) CA12CA1CA9MAP1LC3BMAP1LC3A
SCHEMBL29947213 0.89 CA12 (0.64) CA12CA1CA9MAP1LC3BMAP1LC3A
SCHEMBL29758957 0.89 CA12 (0.64) CA12CA1CA9MAP1LC3BMAP1LC3A
SCHEMBL4757393 0.88 MAP1LC3B (0.42) CA12CA1CA9MAP1LC3BMAP1LC3A
SCHEMBL3258147 0.86 CA12 (0.56) CA12CA1CA9KDM4EALDH1A1
SCHEMBL11442830 0.86 CA12 (0.56) CA12CA1CA9KDM4EALDH1A1
SCHEMBL29544308 0.86 CA12 (0.56) CA12CA1CA9KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492422-B2 Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment Sunbird Bio, Inc. (US) 2025-12-09 US disclosed
US-12090181-B2 Bifidobacterium genus bacterium MORINAGA MILK INDUSTRY CO., LTD. (JP) 2024-09-17 US disclosed
US-11851697-B2 Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment GLYMPSE BIO, INC. (US) 2023-12-26 US disclosed
CN-110506105-B Novel bacterium belonging to the genus Bifidobacterium 森永乳业株式会社 2023-03-24 CN disclosed
US-20230066928-A1 Novel Bifidobacterium Genus Bacterium MORINAGA MILK INDUSTRY CO., LTD. (JP) 2023-03-02 US disclosed
US-11504407-B2 Bifidobacterium genus bacterium MORINAGA MILK INDUSTRY CO., LTD. (JP) 2022-11-22 US disclosed
US-20220128567-A1 EX VIVO PROTEASE ACTIVITY DETECTION FOR DISEASE DETECTION/DIAGNOSTIC, STAGING, MONITORING AND TREATMENT Sunbird Bio, Inc. 2022-04-28 US disclosed
US-20220128546-A1 EX VIVO PROTEASE ACTIVITY DETECTION FOR DISEASE DETECTION/DIAGNOSTIC, STAGING, MONITORING AND TREATMENT Sunbird Bio, Inc. 2022-04-28 US disclosed