Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30011244 | 0.86 | TDP1 (0.50) | ALDH1A1KMT2AKDM4EPOLBRAB9A | |
| SCHEMBL3546695 | 0.78 | NPC1 (0.49) | ALDH1A1KMT2APOLBRAB9ALMNA | |
| SCHEMBL3546699 | 0.78 | NPC1 (0.49) | ALDH1A1KMT2APOLBRAB9ALMNA | |
| SCHEMBL29543790 | 0.77 | BAZ2B (0.39) | ALDH1A1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23245937 | 0.74 | RAB9A (0.49) | ALDH1A1KMT2AKDM4EPOLBRAB9A | |
| SCHEMBL23245988 | 0.74 | RAB9A (0.49) | ALDH1A1KMT2AKDM4EPOLBRAB9A | |
| SCHEMBL23245940 | 0.74 | RAB9A (0.49) | ALDH1A1KMT2AKDM4EPOLBRAB9A | |
| SCHEMBL19127286 | 0.70 | SMN1; SMN2 (0.48) | ALDH1A1KMT2AKDM4EPOLBRAB9A | |
| SCHEMBL28718664 | 0.69 | CYP1A2 (0.43) | ALDH1A1KMT2AKDM4EPOLBRAB9A | |
| SCHEMBL29883915 | 0.69 | CYP1A2 (0.43) | ALDH1A1KMT2AKDM4EPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269742-B | Derivatives of 4- (imidazo [1,2-a ] pyridin-3-yl) -N- (pyridinyl) pyrimidin-2-amine as therapeutic agents | 常州千红生化制药股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| EP-3997088-A1 | DERIVATIVES OF 4-(IMIDAZO[L,2-A]PYRIDIN-3-YL)-N-(PYRIDINYL)PYRIMIDIN- 2-AMINE AS THERAPEUTIC AGENTS | Aucentra Therapeutics Pty Ltd (AU) | 2022-05-18 | — | — | EP | disclosed |