Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 3/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29545124 | 1.00 | USP7 (0.35) | USP7RPS6KA3ACVR1PIK3C3KCNH2 | |
| SCHEMBL29544573 | 0.84 | PIK3C3 (0.31) | USP7PIK3C3KCNH2 | |
| SCHEMBL29544560 | 0.84 | PIK3C3 (0.31) | USP7PIK3C3KCNH2 | |
| SCHEMBL29544718 | 0.79 | TYK2 (0.32) | — | |
| SCHEMBL29544520 | 0.78 | USP7 (0.38) | USP7ACVR1PDPK1PARP1 | |
| SCHEMBL29544635 | 0.77 | NCF1 (0.38) | ACVR1 | |
| SCHEMBL29544676 | 0.77 | NCF1 (0.38) | ACVR1 | |
| SCHEMBL29545540 | 0.76 | NCF1 (0.39) | ACVR1 | |
| SCHEMBL29544629 | 0.76 | NCF1 (0.39) | ACVR1 | |
| SCHEMBL29544372 | 0.75 | GRM2 (0.36) | PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |