Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 4/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29544676 | 1.00 | NCF1 (0.38) | NCF1SRCPRKDCERBB2PDGFRA | |
| SCHEMBL29544629 | 0.87 | NCF1 (0.39) | NCF1ACVR1 | |
| SCHEMBL29545540 | 0.87 | NCF1 (0.39) | NCF1ACVR1 | |
| SCHEMBL29544338 | 0.87 | GRM2 (0.36) | — | |
| SCHEMBL29544372 | 0.87 | GRM2 (0.36) | — | |
| SCHEMBL29544776 | 0.82 | CSF1R (0.38) | SRCERBB2PDGFRAKDRACVR1 | |
| SCHEMBL29545067 | 0.82 | CSF1R (0.38) | SRCERBB2PDGFRAKDRACVR1 | |
| SCHEMBL29544467 | 0.82 | CSF1R (0.38) | SRCERBB2PDGFRAKDRACVR1 | |
| SCHEMBL29545124 | 0.77 | USP7 (0.35) | ACVR1 | |
| SCHEMBL29544665 | 0.77 | USP7 (0.35) | ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |