Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 13/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29544758 | 0.93 | EGFR (0.39) | TYK2RIPK3RORCTGFBR1CDK9 | |
| SCHEMBL29544580 | 0.89 | TYK2 (0.37) | TYK2 | |
| SCHEMBL29545505 | 0.88 | IRAK4 (0.41) | TYK2RIPK3IRAK4TGFBR1MKNK2 | |
| SCHEMBL29544781 | 0.86 | CCNT1 (0.34) | TYK2CDK9 | |
| SCHEMBL29544735 | 0.86 | CCNT1 (0.34) | TYK2CDK9 | |
| SCHEMBL29544663 | 0.84 | RIPK3 (0.36) | RIPK3IRAK4ABL1RORCTGFBR1 | |
| SCHEMBL29545142 | 0.83 | CSF1R (0.39) | TYK2ABL1CDK9 | |
| SCHEMBL29544981 | 0.82 | EGFR (0.36) | TYK2CDK9 | |
| SCHEMBL29544407 | 0.82 | CCNT1 (0.34) | TYK2CDK9 | |
| SCHEMBL29544972 | 0.81 | EGFR (0.37) | TYK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |