Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 6/20 | 0.36 |
| ▸ | CDK8 | P49336 | 6/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 4/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.34 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29545101 | 0.83 | CSNK1D (0.43) | MAPK14 | |
| SCHEMBL29544561 | 0.82 | MET (0.34) | THRBTGFBR1MAPK14 | |
| SCHEMBL29545167 | 0.80 | PIK3CA (0.32) | THRBTGFBR1MAPK14PARP1 | |
| SCHEMBL29544960 | 0.80 | PARP1 (0.32) | CDC7PARP1 | |
| SCHEMBL29544741 | 0.80 | CDC7 (0.36) | CDC7 | |
| SCHEMBL29544807 | 0.80 | HTR2C (0.33) | CDC7PARP1 | |
| SCHEMBL29544520 | 0.79 | USP7 (0.38) | CDC7PARP1 | |
| SCHEMBL29544593 | 0.76 | CDC7 (0.52) | CDK8CDC7PARP1DYRK1AKDM5B | |
| SCHEMBL29545095 | 0.76 | USP7 (0.41) | CDC7THRBTGFBR1MAPK14PARP1 | |
| SCHEMBL31729065 | 0.74 | CDC7 (0.32) | CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |