Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31412648 | 0.85 | KDM4C (0.38) | HPGDSALDH1A1MAPK1KDM4CCCNC | |
| SCHEMBL17129029 | 0.85 | DUSP3 (0.48) | HPGDSALDH1A1MAPK1ALOX5SMN1; SMN2 | |
| SCHEMBL31728612 | 0.79 | CCNC (0.45) | ALDH1A1KDM4CCCNCCDK8MEN1 | |
| SCHEMBL11070855 | 0.73 | RAB9A (0.50) | ALDH1A1MAPK1KDM4CSMN1; SMN2MEN1 | |
| SCHEMBL9986229 | 0.71 | MAPK1 (0.58) | MAPK1MAP2K4 | |
| SCHEMBL24963537 | 0.71 | PDE1A (0.42) | MAPK1PDE1APDE1BPDE3BPDE1C | |
| SCHEMBL29749406 | 0.71 | KDM4C (0.65) | ALDH1A1MAPK1KDM4CSMN1; SMN2MEN1 | |
| SCHEMBL23294471 | 0.71 | KDM4C (0.50) | ALDH1A1MAPK1KDM4CMEN1HPGD | |
| SCHEMBL1919617 | 0.69 | CDC7 (0.49) | ALDH1A1MAPK1RAF1CYP46A1HPGD | |
| SCHEMBL7978314 | 0.69 | KDM4C (0.53) | ALDH1A1MAPK1KDM4CSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022072634-A1 | BICYCLIC COMPOUNDS FOR USE IN THE TREATMENT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-04-07 | — | — | WO | disclosed |