Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24166971 | 1.00 | WDR5 (1.00) | WDR5KMT2A | |
| SCHEMBL24166602 | 0.90 | WDR5 (0.85) | WDR5KMT2A | |
| SCHEMBL29545444 | 0.90 | WDR5 (0.85) | WDR5KMT2A | |
| SCHEMBL24429941 | 0.90 | WDR5 (1.00) | WDR5KMT2A | |
| SCHEMBL28845843 | 0.89 | WDR5 (0.86) | WDR5KMT2A | |
| SCHEMBL29890884 | 0.89 | WDR5 (0.86) | WDR5KMT2A | |
| SCHEMBL24166284 | 0.89 | WDR5 (0.86) | WDR5KMT2A | |
| SCHEMBL24166669 | 0.87 | WDR5 (0.83) | WDR5KMT2A | |
| SCHEMBL24166667 | 0.87 | WDR5 (0.83) | WDR5KMT2A | |
| SCHEMBL29544570 | 0.87 | WDR5 (0.83) | WDR5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12453731-B2 | Aniline-based WDR5 protein-protein interaction inhibitor, and preparation method and use thereof | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2025-10-28 | — | — | US | disclosed |
| CN-109734674-B | Aniline WDR5 protein-protein interaction inhibitor and preparation method and application thereof | 中国药科大学 | 2022-08-26 | — | — | CN | disclosed |
| US-20220152027-A1 | ANILINE-BASED WDR5 PROTEIN-PROTEIN INTERACTION INHIBITOR, AND PREPARATION METHOD AND USE THEREOF | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12453731-B2 | Aniline-based WDR5 protein-protein interaction inhibitor, and preparation method and use thereof | MLLT1, WDR77, MLLT3 | WDR5 4/4885KMT2A 38/4885 |
| US-20220152027-A1 | ANILINE-BASED WDR5 PROTEIN-PROTEIN INTERACTION INHIBITOR, AND PREPARATION METHOD AND USE THEREOF | MLLT1, WDR77, MLLT3 | WDR5 4/4885KMT2A 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.