Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 6/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18554967 | 1.00 | ICMT (0.39) | ICMTCFDPTGDR2ALDH1A1KDM4E | |
| SCHEMBL29841081 | 0.87 | ICMT (0.38) | ICMTCFDALDH1A1KDM4EGRIN2B | |
| SCHEMBL18591239 | 0.87 | ICMT (0.38) | ICMTCFDALDH1A1KDM4EGRIN2B | |
| SCHEMBL18555286 | 0.84 | ICMT (0.43) | ICMTCFDPTGDR2ALDH1A1KDM4E | |
| SCHEMBL29546024 | 0.84 | ICMT (0.43) | ICMTCFDPTGDR2ALDH1A1KDM4E | |
| SCHEMBL18555919 | 0.82 | ICMT (0.45) | ICMTCFDPTGDR2ALDH1A1KDM4E | |
| SCHEMBL29774917 | 0.82 | ICMT (0.45) | ICMTCFDPTGDR2ALDH1A1KDM4E | |
| SCHEMBL29545636 | 0.80 | ICMT (0.48) | ICMTCFDALDH1A1KDM4EGRIN2B | |
| SCHEMBL18554993 | 0.80 | ICMT (0.48) | ICMTCFDALDH1A1KDM4EGRIN2B | |
| SCHEMBL18591230 | 0.80 | MKNK1 (0.44) | ICMTCFDALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114044800-A | Aryl, heteroaryl and heterocyclic compounds for the treatment of medical disorders | 艾其林医药公司 | 2022-02-15 | — | — | CN | disclosed |