Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 4/20 | 0.48 |
| ▸ | CFD | P00746 | 6/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18554993 | 1.00 | ICMT (0.48) | ICMTCFDGRIN2BKMT2AALDH1A1 | |
| SCHEMBL18591169 | 0.91 | ICMT (0.48) | ICMTCFDGRIN2BALOX5APPRMT5 | |
| SCHEMBL18591224 | 0.90 | ICMT (0.47) | ICMTCFDGRIN2BKMT2AALDH1A1 | |
| SCHEMBL18555261 | 0.89 | CFD (0.47) | CFDGRIN2BKMT2AALDH1A1KDM4E | |
| SCHEMBL29545967 | 0.89 | CFD (0.47) | CFDGRIN2BKMT2AALDH1A1KDM4E | |
| SCHEMBL18591230 | 0.86 | MKNK1 (0.44) | ICMTCFDKMT2AALDH1A1KDM4E | |
| SCHEMBL18591234 | 0.85 | ICMT (0.43) | ICMTCFDGRIN2BKMT2AALDH1A1 | |
| SCHEMBL29774878 | 0.85 | ICMT (0.44) | ICMTCFDGRIN2BALDH1A1KDM4E | |
| SCHEMBL18554883 | 0.85 | ICMT (0.44) | ICMTCFDGRIN2BALDH1A1KDM4E | |
| SCHEMBL18591228 | 0.84 | MKNK1 (0.48) | ICMTCFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114044800-A | Aryl, heteroaryl and heterocyclic compounds for the treatment of medical disorders | 艾其林医药公司 | 2022-02-15 | — | — | CN | disclosed |