Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxacillin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.86 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.86 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.66 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxacillin SCHEMBL18048119 | 0.99 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL15387553 | 0.99 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL9876911 | 0.99 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL8722495 | 0.99 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL3817 | 0.99 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL14126543 | 0.99 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL4780815 | 0.99 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL8724789 | 0.99 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL41164 | 0.98 | ALDH1A1 (0.83) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL28965117 | 0.98 | ALDH1A1 (0.83) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4153244-A1 | CIRCULAR RNA COMPOSITIONS AND METHODS | Orna Therapeutics, Inc. (US) | 2023-03-29 | — | — | EP | disclosed |
| CN-109451744-B | Biomarkers for mortality prognosis in critically ill patients | 斯坦福大学托管董事会 | 2022-08-05 | — | — | CN | disclosed |
| CN-114044800-A | Aryl, heteroaryl and heterocyclic compounds for the treatment of medical disorders | 艾其林医药公司 | 2022-02-15 | — | — | CN | disclosed |