Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxacillin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.85 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.65 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.60 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxacillin SCHEMBL8722495 | 1.00 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL9876911 | 1.00 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL18048119 | 1.00 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL15387553 | 1.00 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL14126543 | 1.00 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL8724789 | 1.00 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL4780815 | 1.00 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL41164 | 0.99 | ALDH1A1 (0.83) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL28965117 | 0.99 | ALDH1A1 (0.83) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD | |
| Oxacillin SCHEMBL28938009 | 0.99 | ALDH1A1 (0.83) | ALDH1A1SMN1; SMN2ABCB11CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 33603 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122094963-A | Cardioprotective lipids and methods of use | — | 2026-05-26 | — | — | CN | claimed |
| US-12637481-B2 | Boronic acid derivatives and therapeutic uses thereof | QPEX BIOPHARMA, INC. (US) | 2026-05-26 | — | — | US | claimed |
| WO-2026106551-A1 | ANTIMICROBIAL PEPTIDE NANONETS AND METHODS OF USE THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2026-05-21 | — | — | WO | claimed |
| WO-2026104587-A1 | CYCLIC BORONIC ACID ESTERS USEFUL AS ADJUVANTS IN THE TREATMENT OF BACTERIAL INFECTIONS | ADJUTEC PHARMA AS (NO) | 2026-05-21 | — | — | WO | claimed |
| WO-2026107387-A1 | SYSTEMS AND METHODS FOR MICROBIAL DNA AND RNA DETECTION | DELVE BIO, INC. (US) | 2026-05-21 | — | — | WO | claimed |
| CN-115215923-B | Macrocyclic broad-spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2026-05-19 | — | — | CN | claimed |
| EP-4739326-A2 | PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA | SNIPR Biome ApS (DK) | 2026-05-13 | — | — | EP | claimed |
| EP-4736859-A1 | ANTIBIOTIC COMPOSITIONS | University of Galway (IE) | 2026-05-06 | — | — | EP | claimed |
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| US-20260115234-A1 | PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA | SNIPR BIOME APS (DK) | 2026-04-30 | — | — | US | claimed |
| US-4546076-A | PRODUCTION OF D-ALANINE AND QUANITATIVE ANALYSIS THEREOF | U C B SOCIETE ANONYME (BE) | 1985-10-08 | — | — | US | claimed |
| EP-0152379-A2 | Process for preparing pharmaceutical compositions containing unilamellar liposomes | CIBA-GEIGY AG (CH) | 1985-08-21 | — | — | EP | claimed |
| EP-0026746-B1 | COMBINATORY COMPOSITIONS FOR USE IN A METHOD FOR ENHANCING THE ACTIVITY OF ANTIBIOTICS, ANTIBIOTIC PREPARATIONS HAVING ENHANCED ACTIVITY AND PROCESS FOR THEIR PRODUCTION | CIBA-GEIGY AG (CH) | 1985-04-10 | — | — | EP | claimed |
| US-4442133-A | Antibiotic bonding of vascular prostheses and other implants | UNIVERSITY OF MEDICINE AND DENTISTRY OF , 100 BERGEN STREET, NEWARK, NEW JERSEY, 07103 | 1984-04-10 | — | — | US | claimed |
| EP-0088943-A2 | Composition for the resorption of injected antibacterial substances and mixtures containing a benzyl amine derivative | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 1983-09-21 | — | — | EP | claimed |
| US-4324783-A | SYNERGISTIC COMBINATION OF PENCILLINS | TOYAMA CHEMICAL CO., LTD. (JP) | 1982-04-13 | — | — | US | claimed |
| EP-0026746-A1 | Combinatory compositions for use in a method for enhancing the activity of antibiotics, antibiotic preparations having enhanced activity and process for their production | CIBA-GEIGY AG (CH) | 1981-04-08 | — | — | EP | claimed |
| US-4239745-A | INCUBATION WITH TAGGED ANTIBIOTIC AND ANTIBIOTIC SENSITIVE CELLS | PENICILLIN ASSAYS, INC. (US) | 1980-12-16 | — | — | US | claimed |
| US-4217274-A | Methoxyethoxymethyl esters of penicillins | BRISTOL-MYERS COMPANY (US) | 1980-08-12 | — | — | US | claimed |
| US-4199566-A | DERIVATIVES OF PENICILLANIC ACID | TOYAMA CHEMICAL COMPANY, LIMITED (JP) | 1980-04-22 | — | — | US | claimed |