Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.39 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27210212 | 1.00 | CYP2D6 (0.44) | CYP2D6HSD17B10THRBOGACA2 | |
| SCHEMBL18241081 | 0.98 | CYP2D6 (0.47) | CYP2D6HSD17B10THRBOGACA2 | |
| SCHEMBL18241062 | 0.98 | CYP2D6 (0.47) | CYP2D6HSD17B10THRBOGACA2 | |
| SCHEMBL21518246 | 0.85 | LMNA (0.53) | CYP2D6HSD17B10THRBCA2CYP3A4 | |
| SCHEMBL29546395 | 0.82 | CYP2D6 (0.43) | CYP2D6HSD17B10THRBOGACA2 | |
| SCHEMBL18040614 | 0.81 | CYP2D6 (0.49) | CYP2D6HSD17B10THRBOGACA2 | |
| SCHEMBL21518244 | 0.81 | LMNA (0.49) | CYP2D6HSD17B10THRBCYP3A4LGALS8 | |
| SCHEMBL20564373 | 0.81 | CA12 (0.38) | CYP2D6HSD17B10THRBCA2CYP3A4 | |
| SCHEMBL2620625 | 0.81 | CA12 (0.38) | CYP2D6HSD17B10THRBCA2CYP3A4 | |
| SCHEMBL20705442 | 0.81 | CA12 (0.38) | CYP2D6HSD17B10THRBCA2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232455-A2 | NOVEL LIGANDS FOR ASIALOGLYCOPROTEIN RECEPTOR | Sanofi (FR) | 2023-08-30 | — | — | EP | disclosed |
| CN-116368146-A | Novel ligands for asialoglycoprotein receptors | 赛诺菲 | 2023-06-30 | — | — | CN | disclosed |
| WO-2022084331-A2 | NOVEL LIGANDS FOR ASIALOGLYCOPROTEIN RECEPTOR | SANOFI (FR) | 2022-04-28 | — | — | WO | disclosed |