Pyridoxal

Pyridoxal

SCHEMBL29546256

[2H]C(O)c1cnc(C)c(O)c1C=O

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 10/20 0.78
▸ ALDH1A1 P00352 8/20 0.78
▸ LMNA P02545 6/20 0.78
▸ HPGD P15428 5/20 0.78
▸ MEN1 O00255 3/20 0.78
▸ KMT2A Q03164 3/20 0.78
▸ AOX1 Q06278 1/20 0.78
▸ TRIM24 O15164 1/20 0.76
▸ TRIM33 Q9UPN9 1/20 0.76
▸ ESR1 P03372 1/20 0.60
▸ PTGS1 P23219 1/20 0.60
▸ ACP1 P24666 1/20 0.60
▸ PDE4A P27815 1/20 0.60
▸ P2RX1 P51575 1/20 0.60
▸ P2RX2 Q9UBL9 1/20 0.60
▸ PDXK O00764 1/20 0.54
▸ HSD17B10 Q99714 1/20 0.47
▸ ERN1 O75460 1/20 0.41
▸ HTT P42858 6/20 0.41
▸ MAPT P10636 5/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridoxal SCHEMBL29906 0.88 KDM4E (1.00) KDM4EALDH1A1LMNAHPGDMEN1
Pyridoxal SCHEMBL29389313 0.86 KDM4E (0.97) KDM4EALDH1A1LMNAHPGDMEN1
Pyridoxal SCHEMBL5416120 0.86 KDM4E (0.97) KDM4EALDH1A1LMNAHPGDMEN1
Pyridoxal SCHEMBL27587627 0.86 KDM4E (0.97) KDM4EALDH1A1LMNAHPGDMEN1
Pyridoxal SCHEMBL4668019 0.86 KDM4E (0.97) KDM4EALDH1A1LMNAHPGDMEN1
Pyridoxal SCHEMBL8533734 0.86 KDM4E (0.97) KDM4EALDH1A1LMNAHPGDMEN1
Pyridoxal SCHEMBL50601 0.86 TRIM24 (1.00) KDM4EALDH1A1LMNAHPGDMEN1
Pyridoxal SCHEMBL2527773 0.86 KDM4E (0.97) KDM4EALDH1A1LMNAHPGDMEN1
Pyridoxal SCHEMBL30963032 0.86 KDM4E (0.97) KDM4EALDH1A1LMNAHPGDMEN1
Pyridoxal SCHEMBL27968521 0.86 KDM4E (0.97) KDM4EALDH1A1LMNAHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345299-A1 COMBINATION AND COMPOSITION COMPRISING NICOTINIC ACID OR DERIVATIVE THEREOF AND FATTY ACID OR DERIVATIVE THEREOF T OMEGA AS (NO) 2025-11-13 — — US disclosed
US-20240390412-A1 USE OF DEXTRAN SULFATE TX MEDIC AB (SE) 2024-11-28 — — US disclosed
US-12076337-B2 Method for dissolving scars with dextran sulfate TX MEDIC AB (SE) 2024-09-03 — — US disclosed
US-20230120722-A1 METHOD FOR DISSOLVING SCARS WITH DEXTRAN SULFATE TX MEDIC AB (SE) 2023-04-20 — — US disclosed
US-11534457-B2 Use of dextran sulfate TX MEDIC AB (SE) 2022-12-27 — — US disclosed
US-20220128542-A1 TREATMENT EFFICIENCY EVALUATION TX MEDIC AB (SE) 2022-04-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250345299-A1 COMBINATION AND COMPOSITION COMPRISING NICOTINIC ACID OR DERIVATIVE THEREOF AND FATTY ACID OR DERIVATIVE THEREOF HADHA, HAGH, HADHB KDM4E 3678/4885ALDH1A1 1208/4885LMNA 2137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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