Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27174776 | 0.92 | KDM4E (0.49) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL29546254 | 0.88 | TAS1R3 (0.46) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL29546317 | 0.88 | ACHE (0.46) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL30479400 | 0.87 | TAS1R3 (0.46) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL27174723 | 0.86 | KDM4E (0.47) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL24941679 | 0.85 | KDM4E (0.58) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL29546774 | 0.85 | KDM4E (0.58) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL18490261 | 0.85 | KDM4E (0.58) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL27174717 | 0.85 | KDM4E (0.51) | TAS1R3TAS1R1KDM4EALDH1A1LMNA | |
| SCHEMBL27174719 | 0.84 | KDM4E (0.50) | TAS1R3TAS1R1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232455-A2 | NOVEL LIGANDS FOR ASIALOGLYCOPROTEIN RECEPTOR | Sanofi (FR) | 2023-08-30 | — | — | EP | disclosed |
| CN-116368146-A | Novel ligands for asialoglycoprotein receptors | 赛诺菲 | 2023-06-30 | — | — | CN | disclosed |
| WO-2022084331-A2 | NOVEL LIGANDS FOR ASIALOGLYCOPROTEIN RECEPTOR | SANOFI (FR) | 2022-04-28 | — | — | WO | disclosed |