Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 4/20 | 0.53 |
| ▸ | BACE1 | P56817 | 12/20 | 0.52 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.49 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29471358 | 0.99 | CALCRL (0.54) | CALCRLBACE1RAMP1BACE2OPRK1 | |
| SCHEMBL30088927 | 0.97 | BACE1 (0.55) | CALCRLBACE1RAMP1BACE2CTSD | |
| SCHEMBL30097906 | 0.94 | CALCRL (0.55) | CALCRLBACE1RAMP1BACE2CTSD | |
| SCHEMBL30682547 | 0.92 | OPRK1 (0.52) | CALCRLOPRK1 | |
| SCHEMBL30603858 | 0.90 | CALCRL (0.53) | CALCRLRAMP1KEAP1 | |
| SCHEMBL29580071 | 0.84 | CALCRL (0.61) | CALCRLBACE1RAMP1 | |
| SCHEMBL30259249 | 0.84 | BACE1 (0.60) | BACE1BACE2CTSD | |
| SCHEMBL29576682 | 0.84 | CALCRL (0.57) | CALCRLRAMP1OPRK1 | |
| SCHEMBL29579573 | 0.83 | CALCRL (0.61) | CALCRLRAMP1OPRK1 | |
| SCHEMBL8142396 | 0.82 | BACE1 (0.49) | CALCRLBACE1BACE2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025128693-A1 | AN ENGINEERED MAMMALIAN NUCLEASE FOR IMPROVED MAPPING OF 3-D GENOME ARCHITECTURE FROM NUCLEOSOME TO CHROMOSOME SCALE | THE ROCKEFELLER UNIVERSITY (US) | 2025-06-19 | — | — | WO | disclosed |
| CN-120005853-A | High-activity Cas enzyme and preparation method and application thereof | 艾迪医学科技(广州)有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-119464263-A | Protein glutaminase mutant, encoding gene, recombinant vector, recombinant bacterium, preparation method and application | 北京化工大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-118853717-A | Method for expressing Mouse ZCWPW protein specific structural domain | 沃臻生物科技(佛山)有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118562761-A | Crystal structure of monkey pox virus thymidine kinase as well as preparation method and application thereof | 重庆医科大学 | 2024-08-30 | — | — | CN | disclosed |
| CN-118388659-A | Method for rapidly preparing multiple MHC-antigen peptide tetramers and application thereof | 苏州系统医学研究所 | 2024-07-26 | — | — | CN | disclosed |
| US-12031146-B2 | Genome editing without nucleases | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2024-07-09 | — | — | US | disclosed |
| EP-2064323-B2 | METHODS OF INCREASING THE CELLULOLYTIC ENHANCING ACTIVITY OF A POLYPEPTIDE | NOVOZYMES INC (US) | 2024-06-19 | — | — | EP | disclosed |
| CN-111593035-B | Polypeptides having glucoamylase activity and polynucleotides encoding same | 诺维信公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-117777313-A | Application of His-SUMO tag in preparation of recombinant HPV18E7 protein | 杭州斯达特生物科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-113549641-B | Ribozyme-mediated polycistronic vector and construction method thereof | 复旦大学 | 2023-12-22 | — | — | CN | disclosed |
| EP-3119895-B1 | GENOME EDITING WITHOUT NUCLEASES | UNIV LELAND STANFORD JUNIOR (US) | 2023-12-20 | — | — | EP | disclosed |
| CN-109563508-B | Targeting in situ protein diversification by site-directed DNA cleavage and repair | 马克思—普朗克科学促进协会公司 | 2023-07-07 | — | — | CN | disclosed |
| US-11608570-B2 | Targeted in situ protein diversification by site directed DNA cleavage and repair | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-03-21 | — | — | US | disclosed |
| US-20220275403-A1 | Methods And Compositions For Enhancing AAV-Mediated Homologous Recombination Using Ribonucleotide Reductase Inhibitors | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2022-09-01 | — | — | US | disclosed |
| EP-4017988-A1 | METHODS AND COMPOSITIONS FOR ENHANCING AAV-MEDIATED HOMOLOGOUS RECOMBINATION USING RIBONUCLEOTIDE REDUCTASE INHIBITORS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-06-29 | — | — | EP | disclosed |
| EP-3491131-B1 | TARGETED IN SITU PROTEIN DIVERSIFICATION BY SITE DIRECTED DNA CLEAVAGE AND REPAIR | MAX PLANCK GESELLSCHAFT (DE) | 2022-05-25 | — | — | EP | disclosed |