SCHEMBL29546622

SCHEMBL29546622

CCCC(=O)NCCc1c2n(c3ccc(OC)cc13)Cc1ccccc1-2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MTNR1A P48039 20/20 1.00
▸ MTNR1B P49286 20/20 1.00
▸ KDM4E B2RXH2 2/20 1.00
▸ ALDH1A1 P00352 2/20 1.00
▸ CYP1A2 P05177 2/20 1.00
▸ CYP3A4 P08684 2/20 1.00
▸ CYP2D6 P10635 2/20 1.00
▸ CYP2C9 P11712 2/20 1.00
▸ HPGD P15428 2/20 1.00
▸ TSHR P16473 2/20 1.00
▸ MAPK1 P28482 2/20 1.00
▸ CYP2C19 P33261 2/20 1.00
▸ NPSR1 Q6W5P4 2/20 1.00
▸ HSD17B10 Q99714 2/20 1.00
▸ TDP1 Q9NUW8 2/20 1.00
▸ MAPT P10636 1/20 1.00
▸ NFKB1 P19838 1/20 1.00
▸ APEX1 P27695 1/20 1.00
▸ HIF1A Q16665 1/20 1.00
▸ GMNN O75496 1/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19612546 1.00 MTNR1A (1.00) MTNR1AMTNR1BKDM4EALDH1A1CYP1A2
Dimethylamine SCHEMBL3248090 0.80 MTNR1A (0.67) MTNR1AMTNR1BKDM4EALDH1A1CYP1A2
SCHEMBL3247827 0.78 MTNR1A (0.67) MTNR1AMTNR1BKDM4EALDH1A1CYP1A2
SCHEMBL4437298 0.74 MTNR1A (0.72) MTNR1AMTNR1BKDM4EALDH1A1CYP1A2
SCHEMBL4430575 0.74 MTNR1A (0.72) MTNR1AMTNR1BKDM4EALDH1A1CYP1A2
SCHEMBL5361550 0.70 MTNR1A (0.67) MTNR1AMTNR1BKDM4EALDH1A1CYP1A2
SCHEMBL6193835 0.69 MTNR1A (0.66) MTNR1AMTNR1BKDM4EALDH1A1CYP1A2
SCHEMBL5367094 0.69 MTNR1A (0.55) MTNR1AMTNR1BKDM4EALDH1A1CYP1A2
SCHEMBL5369933 0.68 MTNR1A (0.54) MTNR1AMTNR1BKDM4EALDH1A1CYP1A2
SCHEMBL6944686 0.68 MTNR1A (0.57) MTNR1AMTNR1BKDM4ETSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492475-B2 Process for the generation of metal- or semimetal-containing films BASF SE 2025-12-09 — — US disclosed
US-12297534-B2 Process for the generation of metal- or semimetal-containing films BASF SE (DE) 2025-05-13 — — US disclosed
CN-116940562-A Acetamido-phenylbenzamide derivatives and methods of use thereof 希华医药有限公司 2023-10-24 — — CN disclosed
EP-4225745-A1 ACETAMIDO-PHENYLBENZAMIDE DERIVATIVES AND METHODS OF USING THE SAME Athenex, Inc. (US) 2023-08-16 — — EP disclosed
US-20230046318-A1 PROCESS FOR THE GENERATION OF METAL- OR SEMIMETAL-CONTAINING FILMS WAYNE STATE UNIVERSITY 2023-02-16 — — US disclosed
US-20220298637-A1 PROCESS FOR THE GENERATION OF METAL- OR SEMIMETAL-CONTAINING FILMS WAYNE STATE UNIVERSITY 2022-09-22 — — US disclosed
WO-2022076662-A1 ACETAMIDO-PHENYLBENZAMIDE DERIVATIVES AND METHODS OF USING THE SAME ATHENEX, INC. (US) 2022-04-14 — — WO disclosed
US-20220106301-A1 ACETAMIDO-PHENYLBENZAMIDE DERIVATIVES AND METHODS OF USING THE SAME Health Hope Pharma Limited (HK) 2022-04-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492475-B2 Process for the generation of metal- or semimetal-containing films NR2E3, NR3C2, NR2C2 MTNR1A 950/4885MTNR1B 1234/4885KDM4E 1962/4885
US-20220106301-A1 ACETAMIDO-PHENYLBENZAMIDE DERIVATIVES AND METHODS OF USING THE SAME ABCB1, ABCC1, UGT2B7 MTNR1A 2016/4885MTNR1B 1436/4885KDM4E 2232/4885
US-20220298637-A1 PROCESS FOR THE GENERATION OF METAL- OR SEMIMETAL-CONTAINING FILMS NR2E3, NR3C2, NR2C2 MTNR1A 950/4885MTNR1B 1234/4885KDM4E 1962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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