Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19642431 | 1.00 | ALDH1A1 (0.43) | ALDH1A1PRKDCRXFP1POLBKDM4E | |
| SCHEMBL19661801 | 0.89 | PRKDC (0.40) | ALDH1A1PRKDCTP53MAOASMN1; SMN2 | |
| SCHEMBL19642342 | 0.89 | ALDH1A1 (0.40) | ALDH1A1PRKDCPOLBTP53LMNA | |
| SCHEMBL19642323 | 0.82 | MAOA (0.43) | ALDH1A1PRKDCMAOAHTR1AHTR7 | |
| SCHEMBL29547740 | 0.81 | MAOA (0.42) | ALDH1A1PRKDCMAOAHTR1AHTR7 | |
| SCHEMBL19662132 | 0.81 | MAOA (0.42) | ALDH1A1PRKDCMAOAHTR1AHTR7 | |
| SCHEMBL19642268 | 0.81 | MAOA (0.42) | ALDH1A1PRKDCMAOAHTR1AHTR7 | |
| SCHEMBL19661802 | 0.79 | IP6K1 (0.39) | ALDH1A1PRKDCTP53MAOAIP6K1 | |
| SCHEMBL19642407 | 0.75 | MAOA (0.42) | ALDH1A1KDM4ELMNAMAOASMN1; SMN2 | |
| SCHEMBL20317279 | 0.75 | MAOA (0.42) | ALDH1A1PRKDCKDM4ELMNAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311860-B | Xanthone derivatives for the treatment or prevention of hepatitis B virus diseases | 豪夫迈·罗氏有限公司 | 2022-04-08 | — | — | CN | claimed |
| CN-109311860-B | Xanthone derivatives for the treatment or prevention of hepatitis B virus diseases | 豪夫迈·罗氏有限公司 | 2022-04-08 | — | — | CN | disclosed |