Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | PRKDC | P78527 | 2/20 | 0.36 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19642440 | 1.00 | MAOB (0.46) | MAOBADORA1PIK3CDPIK3CBELANE | |
| SCHEMBL19662155 | 0.85 | MAOB (0.46) | MAOBADORA1ELANEPRKDC | |
| SCHEMBL29548320 | 0.77 | CYP1A1 (0.36) | ELANEPRKDCKDM4E | |
| SCHEMBL19642363 | 0.77 | CYP1A1 (0.36) | ELANEPRKDCKDM4E | |
| SCHEMBL19642396 | 0.76 | ATP1A1 (0.41) | PRKDCKDM4E | |
| SCHEMBL19661802 | 0.76 | IP6K1 (0.39) | MAOBPIK3CDPIK3CBPRKDC | |
| SCHEMBL30978231 | 0.75 | SMN1; SMN2 (0.47) | ELANEPRKDCKDM4EGAAL3MBTL1 | |
| SCHEMBL19642323 | 0.73 | MAOA (0.43) | PRKDC | |
| SCHEMBL29547740 | 0.72 | MAOA (0.42) | PRKDC | |
| SCHEMBL19642268 | 0.72 | MAOA (0.42) | PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311860-B | Xanthone derivatives for the treatment or prevention of hepatitis B virus diseases | 豪夫迈·罗氏有限公司 | 2022-04-08 | — | — | CN | disclosed |