Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | LPAR1 | Q92633 | 15/20 | 0.52 |
| ▸ | LPAR5 | Q9H1C0 | 15/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6293051 | 0.84 | PARP10 (0.66) | PARP10LPAR1LPAR5DAO | |
| SCHEMBL6289863 | 0.82 | PARP10 (0.63) | PARP10LPAR1LPAR5DAO | |
| SCHEMBL2091496 | 0.81 | PARP10 (0.51) | PARP10LPAR1LPAR5DAO | |
| SCHEMBL3520758 | 0.81 | PARP10 (0.51) | PARP10LPAR1LPAR5DAO | |
| SCHEMBL28770201 | 0.81 | PARP10 (0.56) | PARP10LPAR1LPAR5DAO | |
| SCHEMBL10689395 | 0.81 | PARP10 (0.51) | PARP10LPAR1LPAR5DAO | |
| SCHEMBL507282 | 0.81 | MAOB (0.56) | PARP10LPAR1LPAR5DAO | |
| SCHEMBL6158567 | 0.81 | DAO (0.52) | PARP10LPAR1LPAR5TTRDAO | |
| SCHEMBL2354368 | 0.81 | TTR (0.50) | LTA4HPARP10LPAR1LPAR5TTR | |
| SCHEMBL920137 | 0.81 | PARP10 (0.51) | LTA4HPARP10LPAR1LPAR5DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0179788-B1 | PESTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-06-12 | — | — | EP | claimed |
| EP-0179788-A1 | PESTICIDES. | NAT RES DEV (GB) | 1986-05-07 | — | — | EP | claimed |
| EP-0161921-A2 | Improvements relating to pesticides | BTG INTERNATIONAL LIMITED (GB) | 1985-11-21 | — | — | EP | claimed |
| WO-1985004651-A1 | IMPROVEMENTS RELATING TO PESTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-10-24 | — | — | WO | claimed |
| US-7772237-B2 | Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives | CEPHALON FRANCE (FR) | 2010-08-10 | — | — | US | disclosed |
| US-20090105241-A1 | THIO-SUBSTITUTED TRICYCLIC AND BICYCLIC AROMATIC METHANESULFINYL DERIVATIVES | CEPHALON FRANCE (FR) | 2009-04-23 | — | — | US | disclosed |
| US-7476690-B2 | Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives | CEPHALON FRANCE (FR) | 2009-01-13 | — | — | US | disclosed |
| EP-1735300-A1 | THIO-SUBSTITUTED TRICYCLIC AND BICYCLIC AROMATIC METHANESULFINYL DERIVATIVES | CEPHALON FRANCE (FR) | 2006-12-27 | — | — | EP | disclosed |
| US-20060241119-A1 | Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives | CEPHALON FRANCE (FR) | 2006-10-26 | — | — | US | disclosed |
| US-7119214-B2 | Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives | CEPHALON FRANCE (FR) | 2006-10-10 | — | — | US | disclosed |
| US-20050282821-A1 | Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives | CEPHALON FRANCE (FR) | 2005-12-22 | — | — | US | disclosed |
| WO-2005100345-A1 | THIO-SUBSTITUTED TRICYCLIC AND BICYCLIC AROMATIC METHANESULFINYL DERIVATIVES | CEPHALON FRANCE (FR) | 2005-10-27 | — | — | WO | disclosed |
| EP-1589016-A1 | Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives | CEPHALON FRANCE (FR) | 2005-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282821-A1 | Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives | HTR1A, HTR2A, HTR5A | LTA4H 4281/4885PARP10 3776/4885LPAR1 1585/4885 |
| US-20060241119-A1 | Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives | HTR1A, HTR2A, HTR5A | LTA4H 4281/4885PARP10 3776/4885LPAR1 1585/4885 |
| US-20090105241-A1 | THIO-SUBSTITUTED TRICYCLIC AND BICYCLIC AROMATIC METHANESULFINYL DERIVATIVES | HTR1A, HTR2A, HTR5A | LTA4H 4281/4885PARP10 3776/4885LPAR1 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.